Sebastian Frische

Group Leader

Sebastian Frische
Associate Professor, PhD
More information

RESEARCH
The expression and role of AKAP-KL in collecting duct intercalated cells.

Localization of E3 ubiquitin ligase Cul5 in the kidney.

The role of Cl- for the adaptation of collecting duct intercalated cells to increased acid excretion.

NH4+ excretion and renal acid/base regulation  in Li-intoxication.

RESEARCH INTERESTS
Membrane transporters and signaling systems involved in acid/base regulation.

The interaction between renal regulation of NaCl and acid/base balance.

Paracrine signaling systems in the kidney.

Membrane proteins and regulation systems involved in epithelial transport.

Biology of gasses.

In vivo microscopy.

METHODOLOGIES
Animal experiments.
Light- and laserconfocal- and electron-microscopy.
Immunohistochemistry and immunoelectron microscopy.
Analysis of ul-samples of blood and urine by ion-chromatography.

COLLABORATORS & Centers

Collaborative ongoing projects with the following researchers at Dept of Biomedicine: Søren Nielsen, Jeppe Prætorius, Helle Damkier, Ole Fejerskov, Birgitte Mønster Christensen, Erik Ernst, Morten Skovgaard, Mark West. Numerous other collaborations with researchers at other AU Departments and internationally.

RESEARCH GROUP MEMBERS
Henrik Dimke, PhD, posdoc

 

                                                          

Henvendelse om denne sides indhold: 
Revideret 03.08.2016