Glomerular kidney disease

We try to understand how podocytes respond to injury and how the cross talk between glomerular cells progresses to kidney disease.

Identification of bioactive metabolites and metabolic signaling

We study how the metabolome determines proteome function in the kidney.

Heterogeneity of kidney tissue proteome and function

We develop methods to quantify kidney disease heterogeneity on protein level and use that information to understand disease status in mice and men.

Kidney Systems physiology and mass spectrometry

We integrate physiological parameters with omics data sets to advance physiological concepts, and we apply and develop novel approaches to investigate kidney disease pathology.