Arjmand S, Landau AM, Varastehmoradi B, Andreatini R, Joca S, Wegener G. The intersection of astrocytes and the endocannabinoid system in the lateral habenula: on the fast-track to novel rapid-acting antidepressants. Mol Psychiatry. 2022 May 18. doi: 10.1038/s41380-022-01598-4.
Hartmann A, Vila-Verde C, Guimarães FS, Joca SR, Lisboa SF. The NLRP3 inflammasome in stress response: another target for the promiscuous cannabidiol? Curr Neuropharmacol. 2022 Apr 11. doi: 10.2174/1570159X20666220411101217.
Duarte-Silva E, Oriá AC, Mendonça IP, de Melo MG, Paiva IHR, Maes M, Joca SRL, Peixoto CA. Tiny in size, big in impact: Extracellular vesicles as modulators of mood, anxiety and neurodevelopmental disorders. Neurosci Biobehav Rev. 2022 Apr;135:104582. doi: 10.1016/j.neubiorev.2022.104582.
Schou TM, Joca S, Wegener G, Bay-Richter C. Psychiatric and neuropsychiatric sequelae of COVID-19 - A systematic review. Brain Behav Immun. 2021 Oct;97:328-348. doi: 10.1016/j.bbi.2021.07.018. E
Sartim AG, Marques J, Silveira KM, Gobira PH, Guimarães FS, Wegener G, Joca SR. Co-administration of cannabidiol and ketamine induces antidepressant-like effects devoid of hyperlocomotor side-effects. Neuropharmacology. 2021 Sep 1;195:108679. doi: 10.1016/j.neuropharm.2021.108679.
Sales AJ, Maciel IS, Suavinha ACDR, Joca SRL. Modulation of DNA Methylation and Gene Expression in Rodent Cortical Neuroplasticity Pathways Exerts Rapid Antidepressant-Like Effects.
Mol Neurobiol. 2021 Feb;58(2):777-794. doi: 10.1007/s12035-020-02145-4.
Ribeiro DE, Müller HK, Elfving B, Eskelund A, Joca SR, Wegener G. Antidepressant-like effect induced by P2X7 receptor blockade in FSL rats is associated with BDNF signalling activation.
J Psychopharmacol. 2019 Nov;33(11):1436-1446. doi: 10.1177/0269881119872173.
Ribeiro DE, Roncalho AL, Glaser T, Ulrich H, Wegener G, Joca S. P2X7 Receptor Signaling in Stress and Depression. Int J Mol Sci. 2019 Jun 6;20(11):2778. doi: 10.3390/ijms20112778.
Silote GP, Sartim A, Sales A, Eskelund A, Guimarães FS, Wegener G, Joca S. Emerging evidence for the antidepressant effect of cannabidiol and the underlying molecular mechanisms. J Chem Neuroanat. 2019 Jul;98:104-116. doi: 10.1016/j.jchemneu.2019.04.006.
Sales AJ, Fogaça MV, Sartim AG, Pereira VS, Wegener G, Guimarães FS, Joca SRL. Cannabidiol Induces Rapid and Sustained Antidepressant-Like Effects Through Increased BDNF Signaling and Synaptogenesis in the Prefrontal Cortex. Mol Neurobiol. 2019 Feb;56(2):1070-1081. doi: 10.1007/s12035-018-1143-4.
Diniz CRAF, Casarotto PC, Resstel L, Joca SRL. Beyond good and evil: A putative continuum-sorting hypothesis for the functional role of proBDNF/BDNF-propeptide/mBDNF in antidepressant treatment.
Neurosci Biobehav Rev. 2018 Jul;90:70-83. doi: 10.1016/j.neubiorev.2018.04.001.
Diniz CRAF, Casarotto PC, Fred SM, Biojone C, Castrén E, Joca SRL. Antidepressant-like effect of losartan involves TRKB transactivation from angiotensin receptor type 2 (AGTR2) and recruitment of FYN.Neuropharmacology. 2018 Jun;135:163-171. doi: 10.1016/j.neuropharm.2018.03.011.
Sales AJ, Joca SRL. Antidepressant administration modulates stress-induced DNA methylation and DNA methyltransferase expression in rat prefrontal cortex and hippocampus. Behav Brain Res. 2018 May 2;343:8-15. doi: 10.1016/j.bbr.2018.01.022.
Montezuma K, Biojone C, Lisboa SF, Cunha FQ, Guimarães FS, Joca SR. Inhibition of iNOS induces antidepressant-like effects in mice: pharmacological and genetic evidence. Neuropharmacology. 2012 Jan;62(1):485-91. doi: 10.1016/j.neuropharm.2011.09.004.
Sales AJ, Biojone C, Terceti MS, Guimarães FS, Gomes MV, Joca SR. Antidepressant-like effect induced by systemic and intra-hippocampal administration of DNA methylation inhibitors. Br J Pharmacol. 2011 Nov;164(6):1711-21. doi: 10.1111/j.1476-5381.2011.01489.x.
Zanelati TV, Biojone C, Moreira FA, Guimarães FS, Joca SR. Antidepressant-like effects of cannabidiol in mice: possible involvement of 5-HT1A receptors. Br J Pharmacol. 2010 Jan;159(1):122-8. doi: 10.1111/j.1476-5381.2009.00521.x.