At the Department of Biomedicine, we have great experience and knowledge in studying disease mechanisms and physiology, using myriad of techniques and models. However, with increased knowledge about the human genetic code, there is a need to study new and unknown animal experimental models.
Phenotyping (from greek, phainen= to show) means to investigate and describe the traits that an organism displays, i.e. it’s observable characteristics. These characteristics will change depending on genetic background (genotype) and environment. When studying new genetic animal models, it is thus essential to study the phenotype in order to know the functional consequences of genetic alteration. Additionally, continual phenotyping is important in order to monitor disease progression and for the evaluation of new drugs, both prior to and after intervention. An improved insight into the overall phenotype will elevate the interpretation of scientific results in any publication, adding to the integrative and translational value of the animal model.
With vast amount of experience, but many people specializing and working in different areas of research areas, it is not necessarily easy to know if the technique you need is feasible at the Department of Biomedicine. We aim to centralize the knowledge on where the equipment is, who owns and knows it, how to find help and who to talk to. This way, it will be easier to plan and organize phenotyping as part of your studies. We mainly focus on cardiovascular phenotyping, but also offer advice, guidance and technical assistance on general surgeries, blood sampling and tissue collection.