Publications
Mari, M., Martinez-Vicente, M. & Supported by Women In Autophagy (2026). Autophagy beyond Earth: Dr. Ghada Alsaleh on aging, cells, and space. Autophagy, 22(3), 627-629. https://doi.org/10.1080/15548627.2025.2601858
Cong, Y. & Reggiori, F. (2026). Hijacking a cellular highway: non-lipidated LC3 proteins and PCNT (pericentrin) drive influenza a virus uncoating. Autophagy, 22(2), 439-441. https://doi.org/10.1080/15548627.2025.2572527
Sakai, Y., Behrends, C., Cuervo, A. M., Debnath, J., Izumi, M., Jenny, A., Molinari, M., Nakamura, S., Oku, M., Otegui, M. S., Santambrogio, L., Shen, H.-M., Taguchi, T., Thumm, M., Ushimaru, T., Xie, Z. & Reggiori, F. (2026). Microautophagy: definition, classification, and the complexity of the underlying mechanisms. Autophagy, 22(1), 3-9. https://doi.org/10.1080/15548627.2025.2559687
Sakai, Y., Behrends, C., Debnath, J., Izumi, M., Jenny, A., Molinari, M., Nakamura, S., Oku, M., Otegui, M. S., Santambrogio, L., Shen, H.-M., Taguchi, T., Thumm, M., Ushimaru, T., Xie, Z., Cuervo, A. M. & Reggiori, F. (2026). Microautophagy: current understanding of its molecular mechanisms and functions. Autophagy Reports, 5(1), Article 2626661. https://doi.org/10.1080/27694127.2026.2626661
Mauthe, M., van de Beek, N., Mari, M., Korsten, G., Nobari, P., Castelino, K. B., de Mattos, E. P., Ouhida, I., Dijkstra, J. L., Schipper-Krom, S., de la Ballina, L. R., Mueller, M. R., Simonsen, A., Hipp, M. S., Kapitein, L. C., Kampinga, H. H. & Reggiori, F. (2025). A chaperone-proteasome-based fragmentation machinery is essential for aggrephagy. Nature Cell Biology, 27(9), 1448-1464. https://doi.org/10.1038/s41556-025-01747-1
Mauthe, M., Kampinga, H. & Reggiori, F. (2025). Aggregate fragmentation: the ticket to aggrephagy. Autophagy, 21(12), 3422-3424. https://doi.org/10.1080/15548627.2025.2562893
Kanne, J. V. & Reggiori, F. (2025). A plasmid module for PCR-based gene modification for the accurate measurement of vacuolar delivery of specific proteins in yeast Saccharomyces cerevisiae. Autophagy Reports, 4(1), Article 2511724. https://doi.org/10.1080/27694127.2025.2511724
Gómez-Sánchez, R., Fromme, J. C., Ungermann, C. & Reggiori, F. (2025). Atg2/TRAPPIII-Ypt1 axis: deciphering the phagophore-ERES connection. Autophagy. Advance online publication. https://doi.org/10.1080/15548627.2025.2571682
Javed, R., Mari, M., Trosdal, E., Lopes Alberto Duque, T., Paddar, M., Allers, L., Akepati, P., Mudd, M. H., Reggiori, F. & Deretic, V. (2025). ATG9A controls all stages of autophagosome biogenesis. Autophagy, 21(8), 1859-1861. https://doi.org/10.1080/15548627.2025.2494802
Javed, R., Mari, M., Trosdal, E., Duque, T., Paddar, M. A., Allers, L., Mudd, M. H., Claude-Taupin, A., Akepati, P. R., Hendrix, E., He, Y., Salemi, M., Phinney, B., Uchiyama, Y., Reggiori, F. & Deretic, V. (2025). ATG9A facilitates the closure of mammalian autophagosomes. The Journal of Cell Biology, 224(2), Article e202404047. https://doi.org/10.1083/jcb.202404047
Münz, C., Campbell, G. R., Esclatine, A., Faure, M., Labonte, P., Lussignol, M., Orvedahl, A., Altan-Bonnet, N., Bartenschlager, R., Beale, R., Cirone, M., Espert, L., Jung, J., Leib, D., Reggiori, F., Sanyal, S., Spector, S. A., Thiel, V., Viret, C. ... Wodrich, H. (2025). Autophagy machinery as exploited by viruses. Autophagy Reports, 4(1), Article 2464986. https://doi.org/10.1080/27694127.2025.2464986
Grumati, P., Morozzi, G., Hölper, S., Mari, M., Harwardt, M.-L. I. E., Yan, R., Müller, S., Reggiori, F., Heilemann, M. & Dikic, I. (2025). Correction: Full length RTN3 regulates turnover of tubular endoplasmic reticulum via selective autophagy. eLife, 14. https://doi.org/10.7554/eLife.107151
Hu, L., van der Sluis, R. M., Castelino, K. B., Zhang, B.-C., Ronit, A., Zillinger, T., Werner, M., Jørgensen, S. E., Hansen, A. L., Pedersen, A., Narita, R., Reinert, L. S., Bundgaard, B., Holm, C. K., Cobat, A., Casanova, J.-L., Reggiori, F., Mari, M., Paludan, S. R. ... COVID Human Genetic Effort (2025). Deleterious variants in the autophagy-related gene RB1CC1/FIP200 impair immunity to SARS-CoV-2. Nature Communications, 16(1), Article 10618. https://doi.org/10.1038/s41467-025-65308-8
Gómez-Sánchez, R., Chumpen Ramirez, S., Vargas Duarte, P., Hu, Y., Mari, M., Olschewski, K., Hardenberg, R., Fromme, J. C., Ungermann, C. & Reggiori, F. (2025). Establishment of the phagophore-ERES membrane contact site initiates phagophore elongation. Nature Structural & Molecular Biology, 32(11), 2319-2334. https://doi.org/10.1038/s41594-025-01621-6
Cong, Y., Verlhac, P., Green, B. B., de Vries-Idema, J., Strauss, L. M., Río-Bergé, C., Etzerodt, A., Nejsum, L. N., Huckriede, A. L. W. & Reggiori, F. (2025). Influenza A virus subverts the LC3-pericentrin dynein adaptor complex for host cytoplasm entry. Science Advances, 11(24), Article eadu7602. https://doi.org/10.1126/sciadv.adu7602
Zein, L., Dietrich, M., Balta, D., Bader, V., Scheuer, C., Zellner, S., Weinelt, N., Vandrey, J., Mari, M. C., Behrends, C., Zunke, F., Winklhofer, K. F. & Van Wijk, S. J. L. (2025). Linear ubiquitination at damaged lysosomes induces local NFKB activation and controls cell survival. Autophagy, 21(5), 1075-1095. https://doi.org/10.1080/15548627.2024.2443945
Wedman, J. J., de Vries, L., van Lingen, B., van der Zwaag, M., Gómez-Sánchez, R., Hardenberg, R., Huibers, W., Permentier, H., Strauss, E., Chang, M., Reggiori, F., de Kroon, A. I., Sibon, O. C. M. & Schepers, H. (2025). Opt1 imports CoA precursors as glutathione mixed disulfides. The Journal of Biological Chemistry, 301(9), Article 110503. https://doi.org/10.1016/j.jbc.2025.110503
Thorup, C. V., Jeppesen, C. N. A., Jensen, T. H., Tinggaard, A. B., Hvas, C. L., Rud, C. L., Skou, M. K., Mortensen, J. K., Reggiori, F., Dengjel, J., Wang, J., Farup, J., Jessen, N., Kim, W. Y. & Wiggers, H. (2025). POLYamine treatment in elderly patients with Coronary Artery Disease (POLYCAD): study protocol for a Danish randomised, double-blind, placebo-controlled trial of spermidine treatment versus placebo. Trials, 26(1), Article 452. https://doi.org/10.1186/s13063-025-09176-z
Zhang, B.-C., Pedersen, A., Reinert, L. S., Li, Y., Narita, R., Idorn, M., Hu, L., Skouboe, M. K., Li, S., Maimaitili, M., Ding, X., Cong, Y., Zhao, J., Frémond, M.-L., Mikkelsen, K., Gao, Z., Huang, J.-R., Thomsen, E. A., Mikkelsen, J. H. ... Paludan, S. R. (2025). STING signals to NF-κB from late endolysosomal compartments using IRF3 as an adaptor. Nature Immunology, 26(11), 1916-1930. https://doi.org/10.1038/s41590-025-02283-8
Filali-Mouncef, Y., Leytens, A., Vargas Duarte, P., Zampieri, M., Dengjel, J. & Reggiori, F. (2024). An APEX2-based proximity-dependent biotinylation assay with temporal specificity to study protein interactions during autophagy in the yeast Saccharomyces cerevisiae. Autophagy, 20(10), 2323-2337. https://doi.org/10.1080/15548627.2024.2366749