Publications
Javed, R., Mari, M., Trosdal, E., Lopes Alberto Duque, T., Paddar, M., Allers, L., Akepati, P., Mudd, M. H., Reggiori, F. & Deretic, V. (2025). ATG9A controls all stages of autophagosome biogenesis. Autophagy. Advance online publication. https://doi.org/10.1080/15548627.2025.2494802
Javed, R., Mari, M., Trosdal, E., Duque, T., Paddar, M. A., Allers, L., Mudd, M. H., Claude-Taupin, A., Akepati, P. R., Hendrix, E., He, Y., Salemi, M., Phinney, B., Uchiyama, Y., Reggiori, F. & Deretic, V. (2025). ATG9A facilitates the closure of mammalian autophagosomes. The Journal of Cell Biology, 224(2), Article e202404047. https://doi.org/10.1083/jcb.202404047
Zein, L., Dietrich, M., Balta, D., Bader, V., Scheuer, C., Zellner, S., Weinelt, N., Vandrey, J., Mari, M. C., Behrends, C., Zunke, F., Winklhofer, K. F. & Van Wijk, S. J. L. (2025). Linear ubiquitination at damaged lysosomes induces local NFKB activation and controls cell survival. Autophagy, 21(5), 1075-1095. https://doi.org/10.1080/15548627.2024.2443945
Filali-Mouncef, Y., Leytens, A., Vargas Duarte, P., Zampieri, M., Dengjel, J. & Reggiori, F. (2024). An APEX2-based proximity-dependent biotinylation assay with temporal specificity to study protein interactions during autophagy in the yeast Saccharomyces cerevisiae. Autophagy, 20(10), 2323-2337. https://doi.org/10.1080/15548627.2024.2366749
Tan, Y., Lai, T., Li, Y., Tang, Q., Zhang, W., Liu, Q., Wu, S., Peng, X., Sui, X., Reggiori, F., Jiang, X., Chen, Q. & Wang, C. (2024). An oil-in-gel type of organohydrogel loaded with methylprednisolone for the treatment of secondary injuries following spinal cord traumas. Journal of Controlled Release, 374, 505-524. https://doi.org/10.1016/j.jconrel.2024.08.033
Aguilera, M. O., Delgui, L. R., Reggiori, F., Romano, P. S. & Colombo, M. I. (2024). Autophagy as an innate immunity response against pathogens: a Tango dance. FEBS Letters, 598(1), 140-166. https://doi.org/10.1002/1873-3468.14788
Barz, S., Hofmann, K., Reggiori, F. & Kraft, C. (2024). Beyond the C-terminal glycine of ATG8 proteins - The story of some neglected amino acids. Journal of Molecular Biology, 436(15), 168588. Article 168588. https://doi.org/10.1016/j.jmb.2024.168588
Bhattacharya, A., Torggler, R., Reiter, W., Romanov, N., Licheva, M., Ciftci, A., Mari, M., Kolb, L., Kaiser, D., Reggiori, F., Ammerer, G., Hollenstein, D. M. & Kraft, C. (2024). Decoding the function of Atg13 phosphorylation reveals a role of Atg11 in bulk autophagy initiation. EMBO Reports, 25(2), 813-831. https://doi.org/10.1038/s44319-023-00055-9
Cóppola Segovia, V. & Reggiori, F. (2024). Molecular insights into aggrephagy: Their cellular functions in the context of neurodegenerative diseases. Journal of Molecular Biology, 436(15), Article 168493. https://doi.org/10.1016/j.jmb.2024.168493
Kraft, C. & Reggiori, F. (2024). Phagophore closure, autophagosome maturation and autophagosome fusion during macroautophagy in the yeast Saccharomyces cerevisiae. FEBS Letters, 598(1), 73-83. https://doi.org/10.1002/1873-3468.14720
Wang, C., Zhang, B., Cong, Y., Du, X., Chen, S., Visser, L., Ruiz-Moreno, A., Zhang, L., Reggiori, F., Alexander, D. & Groves, M. R. (2024). Small-Molecule Allosteric Inhibitors of Human Aspartate Transcarbamoylase Suppress Proliferation of Bone Osteosarcoma Epithelial Cells. ChemMedChem, 19(13), e202300688. Article e202300688. https://doi.org/10.1002/cmdc.202300688
Füllbrunn, N., Nicastro, R., Mari, M., Griffith, J., Herrmann, E., Rasche, R., Borchers, A.-C., Auffarth, K., Kümmel, D., Reggiori, F., De Virgilio, C., Langemeyer, L. & Ungermann, C. (2024). The GTPase activating protein Gyp7 regulates Rab7/Ypt7 activity on late endosomes. The Journal of Cell Biology, 223(6), Article e202305038. https://doi.org/10.1083/jcb.202305038
Chumpen Ramirez, S., Gómez-Sánchez, R., Verlhac, P., Hardenberg, R., Margheritis, E., Cosentino, K., Reggiori, F. & Ungermann, C. (2023). Atg9 interactions via its transmembrane domains are required for phagophore expansion during autophagy. Autophagy, 19(5), 1459-1478. https://doi.org/10.1080/15548627.2022.2136340
Mauthe, M., Kampinga, H. H., Hipp, M. S. & Reggiori, F. (2023). Digest it all: the lysosomal turnover of cytoplasmic aggregates. Trends in Biochemical Sciences, 48(3), 216-228. https://doi.org/10.1016/j.tibs.2022.09.012
Río-Bergé, C., Cong, Y. & Reggiori, F. (2023). Getting on the right track: Interactions between viruses and the cytoskeletal motor proteins. Traffic, 24(3), 114-130. https://doi.org/10.1111/tra.12835
Foronda, H., Fu, Y., Covarrubias-Pinto, A., Bocker, H. T., González, A., Seemann, E., Franzka, P., Bock, A., Bhaskara, R. M., Liebmann, L., Hoffmann, M. E., Katona, I., Koch, N., Weis, J., Kurth, I., Gleeson, J. G., Reggiori, F., Hummer, G., Kessels, M. M. ... Hübner, C. A. (2023). Heteromeric clusters of ubiquitinated ER-shaping proteins drive ER-phagy. Nature, 618(7964), 402-410. https://doi.org/10.1038/s41586-023-06090-9
Javed, R., Jain, A., Duque, T., Hendrix, E., Paddar, M. A., Khan, S., Claude-Taupin, A., Jia, J., Allers, L., Wang, F., Mudd, M., Timmins, G., Lidke, K., Rusten, T. E., Akepati, P. R., He, Y., Reggiori, F., Eskelinen, E.-L. & Deretic, V. (2023). Mammalian ATG8 proteins maintain autophagosomal membrane integrity through ESCRTs. The EMBO Journal, 42(14), Article e112845. https://doi.org/10.15252/embj.2022112845
Echavarria-Consuegra, L., Dinesh Kumar, N., van der Laan, M., Mauthe, M., Van de Pol, D., Reggiori, F. & Smit, J. M. (2023). Mitochondrial protein BNIP3 regulates Chikungunya virus replication in the early stages of infection. PLOS Neglected Tropical Diseases , 17(11), ´. Article e0010751. https://doi.org/10.1371/journal.pntd.0010751
Zhou, J., Rasmussen, N. L., Olsvik, H. L., Akimov, V., Hu, Z., Evjen, G., Kaeser-Pebernard, S., Sankar, D. S., Roubaty, C., Verlhac, P., van de Beck, N., Reggiori, F., Abudu, Y. P., Blagoev, B., Lamark, T., Johansen, T. & Dengjel, J. (2023). TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1. The Journal of Cell Biology, 222(2), Article e202108144. https://doi.org/10.1083/jcb.202108144
Arlt, H., Raman, B., Filali-Mouncef, Y., Hu, Y., Leytens, A., Hardenberg, R., Guimarães, R., Kriegenburg, F., Mari, M., Smaczynska-de Rooij, I. I., Ayscough, K. R., Dengjel, J., Ungermann, C. & Reggiori, F. (2023). The dynamin Vps1 mediates Atg9 transport to the sites of autophagosome formation. The Journal of Biological Chemistry, 299(5), Article 104712. https://doi.org/10.1016/j.jbc.2023.104712