Key publications

  1. Ren F, Narita R, Rashidi AS, Fruhwürth S, Gao Z, Bak RO, Thomsen MK, Verjans GM, Reinert LS, Paludan SR. ER stress induces caspase-2-tBID-GSDME-dependent cell death in neurons lytically infected with herpes simplex virus type 2. EMBO J. 2023. 30:e113118. doi: 10.15252/embj.2022113118.
  2. Fruhwürth S, Reinert LS, Öberg C, Sakr M, Henricsson M, Zetterberg H, Paludan SR. TREM2 is downregulated by HSV1 in microglia and involved in antiviral defense in the brain. Science Advances. 2023. 9:eadf5808. doi: 10.1126/sciadv.adf5808.
  3. Paludan SR, Pradeu T, Master S, Mogensen TH. Constitutive immune mechanisms: mediators of host defence and immune regulation. Nature Reviews Immunology. 2021. 21:137-150. doi: 10.1038/s41577-020-0391-5.