Kalucka-lab

Hansen, L. M. B., Dam, V. S., Guldbrandsen, H. Ø., Staehr, C., Pedersen, T. M., Kalucka, J. M., Beck, H. C., Postnov, D., Lin, L. & Matchkov, V. (2025). Spatial Transcriptomics and Proteomics Profiling After Ischemic Stroke Reperfusion: Insights Into Vascular Alterations. Stroke, 56(4), 1036-1047. https://doi.org/10.1161/STROKEAHA.124.048085

Jovasevic, V., Wood, E. M., Cicvaric, A., Zhang, H., Petrovic, Z., Carboncino, A., Parker, K. K., Bassett, T. E., Moltesen, M., Yamawaki, N., Login, H., Kalucka, J., Sananbenesi, F., Zhang, X., Fischer, A. & Radulovic, J. (2024). Formation of memory assemblies through the DNA-sensing TLR9 pathway. Nature, 628(8006), 145-153. https://doi.org/10.1038/s41586-024-07220-7

Fan, S., Fleischer, J. R., Dokshokova, L., Böhme, L. S., Haas, G., Schmitt, A. M., Gätje, F. B., Emmalie Rosen, L. A., Bohnenberger, H., Ghadimi, M., Cui, B., Xu, X., Kalucka, J. M., Bösch, F., De Oliveira, T. & Conradi, L. C. (2024). High CIB1 expression in colorectal cancer liver metastases correlates with worse survival and the replacement histopathological growth pattern. Molecular Therapy: Oncology, 32(3), Article 200828. https://doi.org/10.1016/j.omton.2024.200828

Kurmasheva, N., Said, A., Wong, B., Kinderman, P., Han, X., Rahimic, A. H. F., Kress, A., Carter-Timofte, M. E., Holm, E., van der Horst, D., Kollmann, C. F., Liu, Z., Wang, C., Hoang, H.-D., Kovalenko, E., Chrysopoulou, M., Twayana, K. S., Ottosen, R. N., Svenningsen, E. B. ... Olagnier, D. (2024). Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways. Nature Communications, 15(1), Article 4096. https://doi.org/10.1038/s41467-024-48422-x

Wälchli, T., Ghobrial, M., Schwab, M., Takada, S., Zhong, H., Suntharalingham, S., Vetiska, S., Gonzalez, D. R., Wu, R., Rehrauer, H., Dinesh, A., Yu, K., Chen, E. L. Y., Bisschop, J., Farnhammer, F., Mansur, A., Kalucka, J., Tirosh, I., Regli, L. ... Radovanovic, I. (2024). Single-cell atlas of the human brain vasculature across development, adulthood and disease. Nature, 632(8025), 603-613. https://doi.org/10.1038/s41586-024-07493-y

de Zeeuw, P., Treps, L., García-Caballero, M., Harjes, U., Kalucka, J., De Legher, C., Brepoels, K., Peeters, K., Vinckier, S., Souffreau, J., Bouché, A., Taverna, F., Dehairs, J., Talebi, A., Ghesquière, B., Swinnen, J., Schoonjans, L., Eelen, G., Dewerchin, M. & Carmeliet, P. (2024). The gluconeogenesis enzyme PCK2 has a non-enzymatic role in proteostasis in endothelial cells. Communications Biology, 7(1), Article 618. https://doi.org/10.1038/s42003-024-06186-6

Carlantoni, C., Liekfeld, L. M. H., Hemkemeyer, S. A., Schreier, D., Saygi, C., Kurelic, R., Cardarelli, S., Kalucka, J., Schulte, C., Beerens, M., Mailer, R. K., Schäffer, T. E., Naro, F., Pellegrini, M., Nikolaev, V. O., Renné, T. & Frye, M. (2024). The phosphodiesterase 2A controls lymphatic junctional maturation via cGMP-dependent notch signaling. Developmental Cell, 59(3), 308-325. https://doi.org/10.1016/j.devcel.2023.12.002

Festa, J., AlZaim, I. & Kalucka, J. (2023). Adipose tissue endothelial cells: insights into their heterogeneity and functional diversity. Current Opinion in Genetics and Development, 81, Article 102055. https://doi.org/10.1016/j.gde.2023.102055

AlZaim, I., Festa, J. & Kalucka, J. (2023). Adipose tissue lymphatic endothelial cells: revisited functions in the modulation of adipose biology. Current Opinion in Physiology, 34, Article 100675. https://doi.org/10.1016/j.cophys.2023.100675

Fleischer, J. R., Schmitt, A. M., Haas, G., Xu, X., Zeisberg, E. M., Bohnenberger, H., Küffer, S., Teuwen, L. A., Karras, P. J., Beißbarth, T., Bleckmann, A., Planque, M., Fendt, S. M., Vermeulen, P., Ghadimi, M., Kalucka, J., De Oliveira, T. & Conradi, L. C. (2023). Molecular differences of angiogenic versus vessel co-opting colorectal cancer liver metastases at single-cell resolution. Molecular Cancer, 22(1), Article 17. https://doi.org/10.1186/s12943-023-01713-1

Joseph, J. V., Blaavand, M. S., Cai, H., Vernejoul, F., Knopper, R. W., Lindhardt, T. B., Skipper, K. A., Axelgaard, E., Reinert, L., Mikkelsen, J. G., Borghammer, P., Degn, S. E., Perouzel, E., Hager, H., Hansen, B., Kalucka, J. M., Vendelbo, M., Paludan, S. R. & Thomsen, M. K. (2023). STING activation counters glioblastoma by vascular alteration and immune surveillance. Cancer Letters, 579, Article 216480. https://doi.org/10.1016/j.canlet.2023.216480

AlZaim, I., de Rooij, L. P. M. H., Sheikh, B. N., Börgeson, E. & Kalucka, J. (2023). The evolving functions of the vasculature in regulating adipose tissue biology in health and obesity. Nature Reviews Endocrinology, 19(12), 691-707. https://doi.org/10.1038/s41574-023-00893-6

Johannsen, E. B., Skakkebæk, A., Kalucka, J. M., Fedder, J., Gravholt, C. H. & Just, J. (2023). The testicular microvasculature in Klinefelter syndrome is immature with compromised integrity and characterized by excessive inflammatory cross-talk. Human reproduction (Oxford, England), 38(12), 2339–2349. https://doi.org/10.1093/humrep/dead224

Vila, I. K., Guha, S., Kalucka, J., Olagnier, D. & Laguette, N. (2022). Alternative pathways driven by STING: From innate immunity to lipid metabolism. Cytokine and Growth Factor Reviews, 68, 54-68. https://doi.org/10.1016/j.cytogfr.2022.08.006

Wang, F., Ding, P., Liang, X., Ding, X., Brandt, C. B., Sjöstedt, E., Zhu, J., Bolund, S., Zhang, L., de Rooij, L. P. M. H., Luo, L., Wei, Y., Zhao, W., Lv, Z., Haskó, J., Li, R., Qin, Q., Jia, Y., Wu, W. ... Luo, Y. (2022). Author Correction: Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level (Nature Communications, (2022), 13, 1, (3620), 10.1038/s41467-022-31388-z). Nature Communications, 13(1), Article 6748. https://doi.org/10.1038/s41467-022-34498-w

AlZaim, I. & Kalucka, J. (2022). Batokine neuregulin 4 promotes atherosclerotic resolution. Nature Metabolism, 4(11), 1440-1441. https://doi.org/10.1038/s42255-022-00669-8

Wang, F., Ding, P., Liang, X., Ding, X., Brandt, C. B., Sjöstedt, E., Zhu, J., Bolund, S., Zhang, L., de Rooij, L. P. M. H., Luo, L., Wei, Y., Zhao, W., Lv, Z., Haskó, J., Li, R., Qin, Q., Jia, Y., Wu, W. ... Luo, Y. (2022). Endothelial cell heterogeneity and microglia regulons revealed by a pig cell landscape at single-cell level. Nature Communications, 13(1), Article 3620. https://doi.org/10.1038/s41467-022-31388-z

Cuypers, A., Teuwen, L. A., Bridgeman, V. L., de Rooij, L. P. M. H., Eelen, G., Dewerchin, M., Cantelmo, A. R., Kalucka, J., Bouché, A., Vinckier, S., Carton, A., Manderveld, A., Vermeulen, P. B., Reynolds, A. R. & Carmeliet, P. (2022). Generation of vessel co-option lung metastases mouse models for single-cell isolation of metastases-derived cells and endothelial cells. STAR Protocols, 3(4), Article 101691. https://doi.org/10.1016/j.xpro.2022.101691