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Uncovering Microbehavioral Patterns in a Genetic Autism Model

This systems neuroscience project investigates social behavior in Shank3 mutant mice, a validated genetic model for autism spectrum disorder (ASD). While these mice show social and motor traits similar to human ASD, a deeper analysis of their microbehavioral patterns could offer more naturalistic insights.

The goals are to further characterize this physiologically relevant ASD model and to evaluate treatment effects using advanced probabilistic machine learning to analyze naturalistic micro-behavioral patterns.

This project will be primarily hosted at the University of Porto with Patricia, and secondments are planned with Linda at AUMC Amsterdam and Kaat at KU Leuven. 

You can find out more about Patricia’s research here: https://www.neuro-ephys.org/pages/Team/