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Department of Biomedicine

Fenton lab

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van der Lubbe, N., Lim, C. H., Meima, M. E., van Veghel, R., Rosenbaek, L. L., Mutig, K., Danser, A. H. J., Fenton, R. A., Zietse, R. & Hoorn, E. J. (2012). Aldosterone does not require angiotensin II to activate NCC through a WNK4-SPAK-dependent pathway. Pflügers Archiv - European Journal of Physiology, 463(6), 853-63. https://doi.org/10.1007/s00424-012-1104-0

Fenton, R. A. (2012). Another conundrum to concentrate on? A J P: Renal Physiology (Online), 303(4), F492-3. https://doi.org/10.1152/ajprenal.00328.2012

Chen, Y., Rice, W., Gu, Z., Li, J., Huang, J., Brenner, M. B., Van Hoek, A., Xiong, J., Gundersen, G. G., Norman, J. C., Hsu, V. W., Fenton, R. A., Brown, D. & Lu, H. A. J. (2012). Aquaporin 2 promotes cell migration and epithelial morphogenesis. Journal of the American Society of Nephrology, 23(9), 1506-17. https://doi.org/10.1681/ASN.2012010079

Jelen, S., Gena, P., Lebeck, J., Rojek, A., Praetorius, J., Frøkiaer, J., Fenton, R. A., Nielsen, S., Calamita, G. & Rützler, M. (2012). Aquaporin-9 and urea transporter-A gene deletions affect urea transmembrane passage in murine hepatocytes. A J P: Gastrointestinal and Liver Physiology (Online), 303(11), G1279-87. https://doi.org/10.1152/ajpgi.00153.2012

Kortenoeven, M., Boone, M., Schweer, H., Fenton, R. A., Wetzels, J. & Deen, P. (2012). A Vasopressin-Induced Change in Prostaglandin Receptor Subtype Expression Provides an Explanation for the Paradoxical Effect of Prostaglandin E2 on Urine Concentration. Abstract from American Society of Nephrology 45th Annual Meeting & Scientific Exposition, San Diego, United States.

Fenton, R. A. & Brown, D. (2012). Brenner and Rector’s; The Kidney: Cell biology of vasopressin action. W. B. Saunders Company.

Nielsen, S., Kwon, T.-H., Fenton, R. A. & Prætorius, J. (2012). Brenner and Rector’s; The Kidney. Anatomy of the kidney. Elsevier Saunders.

Moeller, H. B. & Fenton, R. A. (2012). Cell biology of vasopressin-regulated aquaporin-2 trafficking. Pflügers Archiv - European Journal of Physiology, 464(2), 133-44. https://doi.org/10.1007/s00424-012-1129-4

Rosenbaek, L. L., Assentoft, M., Pedersen, N. B., MacAulay, N. & Fenton, R. A. (2012). Characterization of a novel phosphorylation site in the sodium-chloride cotransporter, NCC. The Journal of Physiology, 590(Pt 23), 6121-39. https://doi.org/10.1113/jphysiol.2012.240986

Saigusa, T., Reichert, R., Guare, J., Siroky, B. J., Gooz, M., Steele, S., Fenton, R. A., Bell, P. D. & Kolb, R. J. (2012). Collecting duct cells that lack normal cilia have mislocalized vasopressin-2 receptors. A J P: Renal Physiology (Online), 302(7), F801-8. https://doi.org/10.1152/ajprenal.00253.2011

Kortenoeven, M., Sinke, A., Hadrup, N., Wetzels, J., Fenton, R. A. & Deen, P. (2012). Demeclocycline attenuates hyponatremia by reducing Adenylate Cyclase and Aquaporin-2 expression in the renal inner medulla. Abstract from 44th Sandbjerg Meeting on Membrane transport, Denmark.

Fenton, R. A. & Prætorius, J. (2012). Handbook of Physiology; Comprehensive Physiology: Molecular physiology of the medullary collecting ducts. Wiley-Blackwell.

Langelueddecke, C., Roussa, E., Fenton, R. A., Wolff, N. A., Lee, W.-K. & Thévenod, F. (2012). Lipocalin-2 (24p3/Neutrophil Gelatinase-associated Lipocalin (NGAL)) Receptor Is Expressed in Distal Nephron and Mediates Protein Endocytosis. Journal of Biological Chemistry, 287(1), 159-69. https://doi.org/10.1074/jbc.M111.308296

van der Lubbe, N., Jansen, P. M., Salih, M., Fenton, R. A., van den Meiracker, A. H., Danser, A. H. J., Zietse, R. & Hoorn, E. J. (2012). The phosphorylated sodium chloride cotransporter in urinary exosomes is superior to prostasin as a marker for aldosteronism. Hypertension, 60(3), 741-8. https://doi.org/10.1161/HYPERTENSIONAHA.112.198135

Bohn, A. B., Norregaard, R., Stødkilde-Jørgensen, L., Wang, Y., Bertelsen, L. B., Fenton, R. A., Matchkov, V. V., Bouzinova, E. V., Horsman, M. R., Frokiaer, J. & Stødkilde-Jørgensen, H. (2012). Treatment with the vascular disrupting agent Combretastatin is associated with impaired AQP2 trafficking and increased urine output. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, R186-R198. https://doi.org/10.1152/ajpregu.00572.2011

Trimpert, C., van den Berg, D. T. M., Fenton, R. A., Klussmann, E. & Deen, P. M. T. (2012). Vasopressin increases S261 phosphorylation in AQP2-P262L, a mutant in recessive nephrogenic diabetes insipidus. Nephrology Dialysis Transplantation, 27(12), 4389-97. https://doi.org/10.1093/ndt/gfs292

van der Lubbe, N., Lim, C. H., Fenton, R. A., Meima, M. E., Jan Danser, A. H., Zietse, R. & Hoorn, E. J. (2011). Angiotensin II induces phosphorylation of the thiazide-sensitive sodium chloride cotransporter independent of aldosterone. Kidney International, 79(1), 66-76. https://doi.org/10.1038/ki.2010.290

Stødkilde, L., Nørregaard, R., Fenton, R. A., Wang, G., Knepper, M. A. & Frøkiær, J. (2011). Bilateral ureteral obstruction induces early downregulation and redistribution of AQP2 and phosphorylated AQP2. American Journal of Physiology: Renal Physiology, 301(1), F226-35. https://doi.org/10.1152/ajprenal.00664.2010

Sands, J. & Fenton, R. A. (2011). Brenner and Rector’s; The Kidney: Urine concentration and dilution. Elsevier Saunders.

Kortenoeven, M., Pedersen, N. B. & Fenton, R. A. (2011). Connecting tubule-selective knockout of AQP2 causes a mild urinary concentrating defect. Abstract from 43rd Sandbjerg Meeting on Membrane Transport.

Røjen, B. A., Poulsen, S. B., Theil, P. K., Fenton, R. A. & Kristensen, N. B. (2011). Effects of dietary nitrogen concentration on messenger RNA expression and protein abundance of urea transporter-B and aquaporins in ruminal papillae from lactating Holstein cows. Journal of Dairy Science, 94(5), 2587-2591. https://doi.org/10.3168/jds.2010-4073

Wolff, N. A., Liu, W., Fenton, R. A., Lee, W.-K., Thévenod, F. & Smith, C. P. (2011). Ferroportin 1 is expressed basolaterally in rat kidney proximal tubule cells and iron excess increases its membrane trafficking. Journal of Cellular and Molecular Medicine, 15(2), 209-19. https://doi.org/10.1111/j.1582-4934.2009.00985.x

Kortenoeven, M., Pedersen, N. B., Miller, L., Nelson, R. & Fenton, R. A. (2011). Genetic ablation of AQP2 in the mouse connecting tubules results in a mild urinary concentrating defect. Abstract from American Society of Nephrology 44th Annual Meeting & Scientific Exposition.

Fenton, R. A. & Praetorius, J. (2011). Molecular physiology of the medullary collecting duct. Comprehensive Physiology, 1(2), 1031-1056. https://doi.org/10.1002/cphy.c100064

Rosenbæk, L. L., Knepper, M. A. & Fenton, R. A. (2011). Novel vasopressin-regulated phosphorylation site of the NaCl co-transporter, NCC. Abstract from Experimental Biology, Washington DC, United States.

Moeller, H. B., Olesen, E. T. B. & Fenton, R. A. (2011). Regulation of the water channel aquaporin-2 by posttranslational modification. American Journal of Physiology: Renal Physiology, 300(5), F1062-73. https://doi.org/10.1152/ajprenal.00721.2010

Olesen, E. T. B., Rützler, M. & Fenton, R. A. (2011). Selective E-prostanoid receptor agonists increase phosphorylation of aquaporin-2 in vitro and ex vivo. Abstract from Experimental Biology, Washington DC, United States.

Hofmeister, M. V., Füchtbauer, E.-M., Fenton, R. A. & Praetorius, J. (2011). The TRPV5 Promoter as a Tool for Generation of Transgenic Mouse Models. Advances in Experimental Medicine and Biology, 704, 277-86. https://doi.org/10.1007/978-94-007-0265-3_15

Olesen, E. T. B., Rützler, M. R., Moeller, H. B., Praetorius, H. A. & Fenton, R. A. (2011). Vasopressin-independent targeting of aquaporin-2 by selective E-prostanoid receptor agonists alleviates nephrogenic diabetes insipidus. Proceedings of the National Academy of Sciences (PNAS), 108(31), 12949-54. https://doi.org/10.1073/pnas.1104691108

Olesen, E. T. B. & Fenton, R. A. (2011). Vasopressin-independent targeting of aquaporin-2 by selective E-prostanoid receptor agonists alleviates nephrogenic diabetes insipidus. Abstract from The Scandinavian Physiological Society Annual Meeting, Bergen, Norway.

Olesen, E. T. B., Rützler, M., Møller, H., Prætorius, H. & Fenton, R. A. (2011). Vasopressin-independent targeting of Aquaporin-2 by selective E-prostanoid receptor agonists alleviates nephrogenic diabetes insipidus. Abstract from 43rd Sandbjerg Meeting on Membrane Transport.

Olesen, E. T. B., Rützler, M. & Fenton, R. A. (2011). Vasopressin-independent targeting of Aquaporin-2 by selective E-prostanoid receptor agonists alleviates nephrogenic diabetes insipidus. Poster session presented at Experimental Biology, Washington DC, United States.

Rieg, T., Tang, T., Murray, F., Schroth, J., Insel, P. A., Fenton, R. A., Hammond, H. K. & Vallon, V. (2010). Adenylate cyclase 6 determines cAMP formation and aquaporin-2 phosphorylation and trafficking in inner medulla. Journal of the American Society of Nephrology, 21(12), 2059-68. https://doi.org/10.1681/ASN.2010040409

Fenton, R. A., Moeller, H. B., Nielsen, S., de Groot, B. L. & Rützler, M. (2010). A plate reader-based method for cell water permeability measurement. American Journal of Physiology: Renal Physiology, 298(1), F224-30. https://doi.org/10.1152/ajprenal.00463.2009

Moeller, H. B. & Fenton, R. A. (2010). Can one Bad Egg' really spoil the batch? American Journal of Physiology (Consolidated), 588(Pt 13), 2283-4. https://doi.org/10.1113/jphysiol.2010.192732

Fenton, R. A., Moeller, H. B., Zelenina, M., Snaebjornsson, M. T., Holen, T. & MacAulay, N. (2010). Differential water permeability and regulation of three aquaporin 4 isoforms. Cellular and Molecular Life Sciences, 67(5), 829-40. https://doi.org/10.1007/s00018-009-0218-9

Møller, H., Praetorius, J., Rützler, M. R. & Fenton, R. A. (2010). Phosphorylation of aquaporin-2 regulates its endocytosis and protein-protein interactions. Proceedings of the National Academy of Sciences (PNAS), 107(1), 424-9. https://doi.org/10.1073/pnas.0910683107

Xie, L., Hoffert, J. D., Chou, C.-L., Yu, M.-J., Pisitkun, T., Knepper, M. A. & Fenton, R. A. (2010). Quantitative analysis of aquaporin-2 phosphorylation. American Journal of Physiology: Renal Physiology, 298(4), F1018-23. https://doi.org/10.1152/ajprenal.00580.2009

Boone, M., Mobasheri, A., Fenton, R. A., van Balkom, B. W. M., Wismans, R., van der Zee, C. E. E. M. & Deen, P. M. T. (2010). The lysosomal trafficking regulator interacting protein-5 localizes mainly in epithelial cells. Journal of Molecular Histology (Print Edition), 41(1), 61-74. https://doi.org/10.1007/s10735-010-9263-9

Hwang, S., Gunaratne, R., Rinschen, M. M., Yu, M.-J., Pisitkun, T., Hoffert, J. D., Fenton, R. A., Knepper, M. A. & Chou, C.-L. (2010). Vasopressin increases phosphorylation of Ser84 and Ser486 in Slc14a2 collecting duct urea transporters. American Journal of Physiology: Renal Physiology, 299(3), F559-67. https://doi.org/10.1152/ajprenal.00617.2009

Pedersen, N. B., Hofmeister, M. V., Rosenbaek, L. L., Nielsen, J. & Fenton, R. A. (2010). Vasopressin induces phosphorylation of the thiazide-sensitive sodium chloride cotransporter in the distal convoluted tubule. Kidney International, 78(2), 160-9. https://doi.org/10.1038/ki.2010.130

Jensen, A. M., Bae, E. H., Fenton, R. A., Nørregaard, R., Nielsen, S., Kim, S. W. & Frøkiær, J. (2009). Angiotensin II regulates V2 receptor and pAQP2 during ureteral obstruction. American Journal of Physiology: Renal Physiology, 296(1), F127-F134. https://doi.org/10.1152/ajprenal.90479.2008

Kwon, T.-H., Nielsen, J., Møller, H., Fenton, R., Nielsen, S. & Frøkiær, J. (2009). Aquaporins in the Kidney. Handbook of Experimental Pharmacology, 190, 95-132. https://doi.org/10.1007/978-3-540-79885-9_5

Fenton, R. (2009). Essential role of vasopressin-regulated urea transport processes in the mammalian kidney. Pflügers Archiv - European Journal of Physiology, 458(1), 169-77. https://doi.org/10.1007/s00424-008-0612-4

Hofmeister, M. V., Fenton, R. & Praetorius, J. (2009). Fluorescence-isolation of mouse late distal convoluted tubules and connecting tubules: effects of vasopressin and vitamin D3 on Ca²⁺ signaling. American Journal of Physiology: Renal Physiology, 296(1), F194-203. https://doi.org/10.1152/ajprenal.90495.2008

Zwang, N. A., Hoffert, J. D., Pisitkun, T., Møller, H., Fenton, R. & Knepper, M. A. (2009). Identification of Phosphorylation-Dependent Binding Partners of Aquaporin-2 Using Protein Mass Spectrometry. Journal of Proteome Research, 8(3), 1540-54. https://doi.org/10.1021/pr800894p

Robben, J. H., Fenton, R. A., Vargas, S. L., Schweer, H., Peti-Peterdi, J., Deen, P. M. T. & Milligan, G. (2009). Localization of the succinate receptor in the distal nephron and its signaling in polarized MDCK cells. Kidney International, 76(12), 1258-67. https://doi.org/10.1038/ki.2009.360

Møller, H., Macaulay, N., Knepper, M. A. & Fenton, R. (2009). Role of multiple phosphorylation sites in the COOH-terminal tail of aquaporin-2 for water transport: evidence against channel gating. American Journal of Physiology: Renal Physiology, 296(3), F649-57. https://doi.org/10.1152/ajprenal.90682.2008

Møller, H., Fenton, R. A., Zeuthen, T. & Macaulay, N. (2009). Vasopressin-dependent short-term regulation of aquaporin 4 expressed in Xenopus oocytes. Neuroscience, 164(4), 1674-84. https://doi.org/10.1016/j.neuroscience.2009.09.072

Rojek, A., Praetorius, J., Frøkiaer, J., Nielsen, S. & Fenton, R. A. (2008). A current view of the mammalian aquaglyceroporins. Annual Review of Physiology, 70, 301-27. https://doi.org/10.1146/annurev.physiol.70.113006.100452

Displaying results 151 to 200 out of 233

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Revised 27.10.2023

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Lena Kjær Rosenbæk