Kortenoeven, M. LA., Cheng, L., Wu, Q. & Fenton, R. A. (2021). An in vivo protein landscape of the mouse DCT during high dietary K⁺ or low dietary Na⁺ intake. American Journal of Physiology: Renal Physiology, 320(5), F908-F921. https://doi.org/10.1152/ajprenal.00064.2021

Olesen, E. T. B. & Fenton, R. A. (2021). Aquaporin 2 regulation: implications for water balance and polycystic kidney diseases. Nature Reviews. Nephrology, 17(11), 765-781. https://doi.org/10.1038/s41581-021-00447-x

Blijdorp, C. J., Tutakhel, O. A. Z., Hartjes, T. A., van den Bosch, T. P. P., van Heugten, M. H., Rigalli, J. P., Willemsen, R., Musterd-Bhaggoe, U. M., Barros, E. R., Carles-Fontana, R., Carvajal, C. A., Arntz, O. J., van de Loo, F. A. J., Jenster, G., Clahsen-van Groningen, M. C., Cuevas, C. A., Severs, D., Fenton, R. A., van Royen, M. E. ... Hoorn, E. J. (2021). Comparing Approaches to Normalize, Quantify, and Characterize Urinary Extracellular Vesicles. Journal of the American Society of Nephrology : JASN, 32(5), 1210-1226. https://doi.org/10.1681/ASN.2020081142

Petrillo, F., Iervolino, A., Angrisano, T., Jelen, S., Costanzo, V., D’Acierno, M., Cheng, L., Wu, Q., Guerriero, I., Mazzarella, M. C., De Falco, A., D’Angelo, F., Ceccarelli, M., Caraglia, M., Capasso, G., Fenton, R. A. & Trepiccione, F. (2021). Dysregulation of Principal Cell miRNAs Facilitates Epigenetic Regulation of AQP2 and Results in Nephrogenic Diabetes Insipidus. Journal of the American Society of Nephrology, 32(6), 1339-1354. https://doi.org/10.1681/ASN.2020010031

Frank Holden, M., Oczachowska-Kulik, A. E., Fenton, R. A. & Bech, J. N. (2021). Effect of furosemide on body composition and urinary proteins that mediate tubular sodium and sodium transport-A randomized controlled trial. Physiological Reports, 8(24), Article e14653. https://doi.org/10.14814/phy2.14653

Abraham, S., Paknikar, R., Bhumbra, S., Luan, D., Venkatareddy, M., O'Connor, C., Bitzer, M., Fenton, R. A., Hurd, T., Garg, P. & Patel, S. R. (2021). Epigenetic regulation of arginine vasopressin receptor 2 expression by PAX2 and Pax transcription interacting protein. American journal of physiology. Renal physiology, 320(3), F404-F417. https://doi.org/10.1152/ajprenal.00371.2020

Kortenoeven, M. L. A., Esteva-Font, C., Dimke, H., Poulsen, S. B., Murali, S. K. & Fenton, R. A. (2021). High dietary potassium causes ubiquitin-dependent degradation of the kidney sodium-chloride cotransporter. The Journal of Biological Chemistry, 297(2), Article 100915. https://doi.org/10.1016/j.jbc.2021.100915

Wu, Q., Poulsen, S., Murali, S., Grimm, P. R., Su, X.-T., Delpire, E., Welling, P., Ellison, D. & Fenton, R. (2021). Large-Scale Proteomic Assessment of Urinary Extracellular Vesicles Highlights Their Reliability in Reflecting Protein Changes in the Kidney. Journal of the American Society of Nephrology, 32(9), 2195-2209. https://doi.org/10.1681/ASN.2020071035

Baasch Christensen, I., Cheng, L., Brewer, J. R., Bartsch, U., Fenton, R. A., H Damkier, H. & Praetorius, J. (2021). Multiple Na,K-ATPase Subunits Colocalize in the Brush Border of Mouse Choroid Plexus Epithelial Cells. International Journal of Molecular Sciences , 22(4), 1-27. Article 1569. https://doi.org/10.3390/ijms22041569

Wu, A., Wolley, M. J., Wu, Q., Gordon, R. D., Fenton, R. A. & Stowasser, M. (2021). The Cl⁻/HCO₃⁻ exchanger pendrin is downregulated during oral co-administration of exogenous mineralocorticoid and KCl in patients with primary aldosteronism. Journal of Human Hypertension, 35(10), 837-848. https://doi.org/10.1038/s41371-020-00439-7

Aroankins, T. S., Murali, S. K., Fenton, R. A. & Wu, Q. (2021). The Hydrogen-Coupled Oligopeptide Membrane Cotransporter Pept2 is SUMOylated in Kidney Distal Convoluted Tubule Cells. Frontiers in Molecular Biosciences, 8, Article 790606. https://doi.org/10.3389/fmolb.2021.790606

Wu, Q. & Fenton, R. A. (2021). Urinary proteomics for kidney dysfunction: insights and trends. Expert Review of Proteomics, 18(6), 437-452. https://doi.org/10.1080/14789450.2021.1950535

Fenton, R. A., Murali, S. K. & Moeller, H. B. (2020). Advances in Aquaporin-2 trafficking mechanisms and their implications for treatment of water balance disorders. American journal of physiology. Cell physiology, 319(1), C1-C10. https://doi.org/10.1152/ajpcell.00150.2020

Xue, J., Thomas, L., Tahmasbi, M., Valdez, A., Dominguez Rieg, J. A., Fenton, R. A. & Rieg, T. (2020). An inducible intestinal epithelial cell-specific NHE3 knockout mouse model mimicking congenital sodium diarrhea. Clinical Science, 134(8), 941-953. https://doi.org/10.1042/CS20200065

Somparn, P., Boonkrai, C., Charngkaew, K., Chomanee, N., Hodge, K. G., Fenton, R. A., Pisitkun, T. & Khositseth, S. (2020). Bilateral ureteral obstruction is rapidly accompanied by ER stress and activation of autophagic degradation of IMCD proteins, including AQP2. American journal of physiology. Renal physiology, 318(1), F135-F147. https://doi.org/10.1152/ajprenal.00113.2019

Xue, J., Thomas, L., Dominguez Rieg, J. A., Fenton, R. A. & Rieg, T. (2020). Genetic deletion of connexin 37 causes polyuria and polydipsia. PLOS ONE, 15(12), Article e0244251. https://doi.org/10.1371/journal.pone.0244251

Christensen, I. B., Wu, Q., Bohlbro, A. S., Skals, M. G., Damkier, H. H., Hübner, C. A., Fenton, R. A. & Praetorius, J. (2020). Genetic disruption of slc4a10 alters the capacity for cellular metabolism and vectorial ion transport in the choroid plexus epithelium. Fluids and Barriers of the CNS, 17(1), Article 2. https://doi.org/10.1186/s12987-019-0162-5

Saglar Ozer, E., Moeller, H. B., Karaduman, T., Fenton, R. A. & Mergen, H. (2020). Molecular characterization of an aquaporin-2 mutation causing a severe form of nephrogenic diabetes insipidus. Cellular and Molecular Life Sciences, 77(5), 953-962. https://doi.org/10.1007/s00018-019-03219-w

Hoorn, E. J., Gritter, M., Cuevas, C. A. & Fenton, R. A. (2020). Regulation of the Renal NaCl Cotransporter and Its Role in Potassium Homeostasis. Physiological Reviews, 100(1), 321-356. https://doi.org/10.1152/physrev.00044.2018

Kalucka, J., de Rooij, L. P. M. H., Goveia, J., Rohlenova, K., Dumas, S. J., Meta, E., Conchinha, N. V., Taverna, F., Teuwen, L.-A., Veys, K., García-Caballero, M., Khan, S., Geldhof, V., Sokol, L., Chen, R., Treps, L., Borri, M., de Zeeuw, P., Dubois, C. ... Carmeliet, P. (2020). Single-Cell Transcriptome Atlas of Murine Endothelial Cells. Cell, 180(4), 764-779.e20. https://doi.org/10.1016/j.cell.2020.01.015

Fenton, R. A., Murali, S. K., Kaji, I., Akiba, Y., Kaunitz, J. D., Kristensen, T. B., Poulsen, S. B., Dominguez Rieg, J. A. & Rieg, T. (2019). Adenylyl cyclase 6 expression is essential for cholera toxin-induced diarrhea. The Journal of Infectious Diseases, 220(11), 1719-1728. https://doi.org/10.1093/infdis/jiz013

Ho, P. Y., Li, H., Cheng, L., Bhalla, V., Fenton, R. A. & Hallows, K. R. (2019). AMPK phosphorylation of the β₁Pix exchange factor regulates the assembly and function of an ENaC inhibitory complex in kidney epithelial cells. American journal of physiology. Renal physiology, 317(6), F1513-F1525. https://doi.org/10.1152/ajprenal.00592.2018

Keppner, A., Maric, D., Sergi, C., Ansermet, C., De Bellis, D., Kratschmar, D. V., Canonica, J., Klusonova, P., Fenton, R. A., Odermatt, A., Crambert, G., Hoogewijs, D. & Hummler, E. (2019). Deletion of the serine protease CAP2/Tmprss4 leads to dysregulated renal water handling upon dietary potassium depletion. Scientific Reports, 9(1), Article 19540. https://doi.org/10.1038/s41598-019-55995-x

Poulsen, S. B. & Fenton, R. A. (2019). K+ and the renin-angiotensin-aldosterone system: new insights into their role in blood pressure control and hypertension treatment. The Journal of Physiology, 597(17), 4451-4464. https://doi.org/10.1113/JP276844

Thomas, L., Xue, J., Murali, S. K., Fenton, R. A., Rieg, J. A. D. & Rieg, T. (2019). Npt2a inhibition in chronic kidney disease. Acta Physiologica, 227. https://doi.org/10.1111/apha.13366

Thomas, L., Xue, J., Murali, S. K., Fenton, R. A., Dominguez Rieg, J. A. & Rieg, T. (2019). Pharmacological Npt2a Inhibition Causes Phosphaturia and Reduces Plasma Phosphate in Mice with Normal and Reduced Kidney Function. Journal of the American Society of Nephrology : JASN, 30(11), 2128-2139. https://doi.org/10.1681/ASN.2018121250

Penton, D., Moser, S., Wengi, A., Czogalla, J., Rosenbaek, L. L., Rigendinger, F., Faresse, N., Martins, J. R., Fenton, R. A., Loffing-Cueni, D. & Loffing, J. (2019). Protein Phosphatase 1 Inhibitor-1 Mediates the cAMP-Dependent Stimulation of the Renal NaCl Cotransporter. Journal of the American Society of Nephrology : JASN, 30(5), 737-750. https://doi.org/10.1681/ASN.2018050540

Smith, C. P., Lee, W.-K., Haley, M., Poulsen, S. B., Thévenod, F. & Fenton, R. A. (2019). Proximal tubule transferrin uptake is modulated by cellular iron and mediated by apical membrane megalin-cubilin complex and transferrin receptor 1. Journal of Biological Chemistry, 294(17), 7025-7036. https://doi.org/10.1074/jbc.RA118.006390

Cheng, L., Poulsen, S. B., Wu, Q., Esteva-Font, C., Olesen, E. T. B., Peng, L., Olde, B., Leeb-Lundberg, L. M. F., Pisitkun, T., Rieg, T., Dimke, H. & Fenton, R. A. (2019). Rapid Aldosterone-Mediated Signaling in the DCT Increases Activity of the Thiazide-Sensitive NaCl Cotransporter. Journal of the American Society of Nephrology : JASN, 30(8), 1454-1470. https://doi.org/10.1681/ASN.2018101025

Raikwar, N., Braverman, C., Snyder, P. M., Fenton, R. A., Meyerholz, D. K., Abboud, F. M. & Harwani, S. C. (2019). Renal denervation and CD161a immune ablation prevent cholinergic hypertension and renal sodium retention. American Journal of Physiology: Heart and Circulatory Physiology, 317(3), H517-H530. https://doi.org/10.1152/ajpheart.00234.2019

Wu, Q., Aroankins, T. S., Cheng, L. & Fenton, R. A. (2019). SUMOylation Landscape of Renal Cortical Collecting Duct Cells. Journal of Proteome Research, 18(10), 3640-3648. https://doi.org/10.1021/acs.jproteome.9b00306

Murali, S. K., Aroankins, T. S., Moeller, H. B. & Fenton, R. A. (2019). The Deubiquitylase USP4 Interacts with the Water Channel AQP2 to Modulate Its Apical Membrane Accumulation and Cellular Abundance. Cells, 8(3). https://doi.org/10.3390/cells8030265

Poulsen, S. B., Marin De Evsikova, C., Murali, S. K., Praetorius, J., Chern, Y., Fenton, R. A. & Rieg, T. (2018). Adenylyl cyclase 6 is required for maintaining acid-base homeostasis. Clinical Science, 132(16), 1779-1796. https://doi.org/10.1042/CS20180060

Rosenbaek, L. L., Rizzo, F., Wu, Q., Rojas-Vega, L., Gamba, G., MacAulay, N., Staub, O. & Fenton, R. A. (2018). Author Correction: The thiazide sensitive sodium chloride co-transporter NCC is modulated by site-specific ubiquitylation. Scientific Reports, 8(1), 4215. Article 4215. https://doi.org/10.1038/s41598-018-22153-8

Moeller, H. B., Fuglsang, C. H., Pedersen, C. N. & Fenton, R. A. (2018). Basolateral cholesterol depletion alters Aquaporin-2 post-translational modifications and disrupts apical plasma membrane targeting. Biochemical and Biophysical Research Communications, 1(1), 157-162. https://doi.org/10.1016/j.bbrc.2017.11.002

Wu, Q., Moeller, H. B., Stevens, D. A., Sanchez-Hodge, R., Childers, G., Kortenoeven, M. L. A., Cheng, L., Rosenbaek, L. L., Rubel, C., Patterson, C., Pisitkun, T., Schisler, J. C. & Fenton, R. A. (2018). CHIP Regulates Aquaporin-2 Quality Control and Body Water Homeostasis. Journal of the American Society of Nephrology, 29(3), 936-948 . https://doi.org/10.1681/ASN.2017050526

Wu, Q. & Fenton, R. A. (2018). Proteomic approaches in kidney disease biomarker discovery. American Journal of Physiology: Renal Physiology, 315(6), F1817-F1821. https://doi.org/10.1152/ajprenal.00421.2018

Poulsen, S. B., Limbutara, K., Fenton, R. A., Pisitkun, T. & Christensen, B. M. (2018). RNA sequencing of kidney distal tubule cells reveals multiple mediators of chronic aldosterone action. Physiological Genomics, 50(5), 343-354. https://doi.org/10.1152/physiolgenomics.00084.2017

Damkier, H. H., Christensen, H. L., Christensen, I. B., Wu, Q., Fenton, R. A. & Praetorius, J. (2018). The murine choroid plexus epithelium expresses the 2Cl-/H+-exchanger ClC-7 and Na+/H+ exchanger NHE6 in the luminal membrane domain. American Journal of Physiology: Cell Physiology, 314(4), C439-C448. https://doi.org/10.1152/ajpcell.00145.2017

Olesen, E. T. B. & Fenton, R. A. (2017). Aquaporin-2 membrane targeting: still a conundrum. American Journal of Physiology: Renal Physiology, 312(4), F744-F747. https://doi.org/10.1152/ajprenal.00010.2017

Rosenbaek, L. L., Rizzo, F., MacAulay, N., Staub, O. & Fenton, R. A. (2017). Functional assessment of sodium chloride cotransporter NCC mutants in polarized mammalian epithelial cells. American Journal of Physiology: Renal Physiology, 313(2), F495-F504. https://doi.org/10.1152/ajprenal.00088.2017

Khositseth, S., Charngkaew, K., Boonkrai, C., Somparn, P., Uawithya, P., Chomanee, N., Payne, D. M., Fenton, R. A. & Pisitkun, T. (2017). Hypercalcemia induces targeted autophagic degradation of aquaporin-2 at the onset of nephrogenic diabetes insipidus. Kidney International, 91(5), 1070-1087. https://doi.org/10.1016/j.kint.2016.12.005

Wolley, M. J., Wu, A., Xu, S., Gordon, R. D., Fenton, R. A. & Stowasser, M. (2017). In Primary Aldosteronism, Mineralocorticoids Influence Exosomal Sodium-Chloride Cotransporter Abundance. Journal of the American Society of Nephrology, 28(1), 56-63. https://doi.org/10.1681/ASN.2015111221

Tutakhel, O. A. Z., Moes, A. D., Valdez-Flores, M. A., Kortenoeven, M. L. A., Vrie, M. V. D., Jeleń, S., Fenton, R. A., Zietse, R., Hoenderop, J. G. J., Hoorn, E. J., Hilbrands, L. & Bindels, R. J. M. (2017). NaCl cotransporter abundance in urinary vesicles is increased by calcineurin inhibitors and predicts thiazide sensitivity. P L o S One, 12(4), e0176220. Article e017622. https://doi.org/10.1371/journal.pone.0176220

Fenton, R. A., Poulsen, S. B., de la Mora Chavez, S., Soleimani, M., Dominguez Rieg, J. A. & Rieg, T. (2017). Renal tubular NHE3 is required in the maintenance of water and sodium chloride homeostasis. Kidney International. Supplement, 92(2), 397-414. https://doi.org/10.1016/j.kint.2017.02.001

Poulsen, S. B., Kristensen, T. B., Brooks, H. L., Kohan, D. E., Rieg, T. & Fenton, R. A. (2017). Role of adenylyl cyclase 6 in the development of lithium-induced nephrogenic diabetes insipidus. JCI Insight, 2(7), e91042. https://doi.org/10.1172/jci.insight.91042

Rutzler, M., Rojek, A., Damgaard, M. V., Andreasen, A., Fenton, R. A. & Nielsen, S. (2017). Temporal deletion of Aqp11 in mice is linked to the severity of cyst-like disease. American Journal of Physiology: Renal Physiology, 312(2), F343-F351. https://doi.org/10.1152/ajprenal.00065.2016

Rosenbaek, L. L., Rizzo, F., Wu, Q., Rojas-Vega, L., Gamba, G., MacAulay, N., Staub, O. & Fenton, R. A. (2017). The thiazide sensitive sodium chloride co-transporter NCC is modulated by site-specific ubiquitylation. Scientific Reports, 7(1), 12981. Article 12981. https://doi.org/10.1038/s41598-017-12819-0

Al-Bataineh, M. M., Li, H., Ohmi, K., Gong, F., Marciszyn, A., Naveed, S., Zhu, X., Neumann, D., Wu, Q., Cheng, L., Fenton, R. A., Pastor-Soler, N. M. & Hallows, K. R. (2016). Activation of the Metabolic Sensor AMP-Activated Protein Kinase Inhibits Aquaporin-2 Function in Kidney Principal Cells. American Journal of Physiology: Renal Physiology, 311(5), ajprenal.00308.2016. https://doi.org/10.1152/ajprenal.00308.2016

Landegren, N., Lindberg, M. P., Skov, J., Hallgren, A., Eriksson, D., Toft-Bertelsen, T. L., MacAulay, N., Hagforsen, E., Räisänen-Sokolowski, A., Saha, H., Nilsson, T., Nordmark, G., Ohlsson, S., Gustafsson, J., Husebye, E. S., Larsson, E., Anderson, M. S., Perheentupa, J., Rorsman, F. ... Kämpe, O. (2016). Autoantibodies targeting a collecting duct-specific water channel in tubulointerstitial nephritis. Journal of the American Society of Nephrology, 27(10), 3220-3228. https://doi.org/10.1681/ASN.2015101126