This project explores the role of anti-lipid antibodies in multiple sclerosis (MS) by analyzing them at the single-antibody level, focusing on their diversity, specificity, and functionality. Using advanced techniques like single-cell microfluidic assays, we will assess anti-lipid antibodies in MS patients to measure affinity and cross-reactivity.
The project will adapt this technology to investigate lipid-specific antibodies in MS.
This project will be primarily hosted at Aarhus University with Klaus, and secondments are planned with Daniela in Milan and Steeves in Bordeaux.