In vivo, immune responses are shaped by individual cells with diverse functionalities. Even within seemingly homogeneous populations, heterogeneity in cell cycle, metabolism, and gene expression generates functional variability, which, together with cellular plasticity, determines response outcomes.
We aim to quantitatively analyze cellular functions at single-cell resolution, developing tools to measure and phenotype individual cells within complex immune responses. Beyond mechanistic insight, this approach has translational potential, enabling improved evaluation of vaccines, immune therapies, and personalized interventions. By studying cells as functional mediators, we can better understand, predict, and manipulate complex cellular responses in health and disease.
At AU, I contribute to teaching across different levels. At the bachelor level, I have participated in teaching the pharmacology course (15 ECTS) for approximately 300 medical students each semester, delivering lectures with associated exercises and supporting examination, as well as the pharmacology and drug development course for molecular medicine students. I have also supervised bachelor students on theoretical and empirical projects, providing one-on-one mentoring and peer feedback. At the doctoral level, I serve as responsible coordinator for the Transcend network. Also, I am in charge of the PhD course for 'From Numbers to Knowledge: Measurement Theory in the Biomedical Sciences' (4.9 ECTS), a new course I have designed for our doctoral students.