Professor Trine Mogensen is one of five central investigators in the Center for Immunology of Viral Infections (CiViA). CiViA is funded by Danish National Research Foundation (DNRF) as a Center of Excellence. The center is hosted by the Department of Biomedicine, Aarhus University (AU), and consists of research groups based at AU and at the Technical University Munich (TUM).
CiViA aims to uncover novel immune mechanisms that contribute to early defense against infections, and to decipher how the delicate balance between protective and pathological immune responses are achieved. In addition, the center aims to intersect experimental research with philosophy of science, and therefore to challenge current paradigms by exploring their rational basis, and propose new ones.
Professor Trine Mogensen is the only Danish member in the steering committee of The COVID Human Genetic Effort: an international consortium aiming to discover: (i) Monogenic inborn errors of immunity (IEI), rare or common, underlying severe forms of COVID-19 in previously healthy individuals (ii) Monogenic variations, rare or common, which make certain individuals resistant to the infection by the SARS-CoV2 itself, despite repeated exposure.
Professor Trine Mogensen is the project leader of PASCAL-MID: a CRISPR/Cas9 research center founded on empirical experience with the technique. The background for the generation of this 'brickless' center is that current treatment options for rare monogenic disorders are expensive and have low success rates.
Professor Trine Mogensen is the managing professor of The Inflammation Network at Aarhus University. The Network focuses on reducing the burden of infectious and inflammatory diseases caused by pathogens, damaged cells, toxic compounds or radiation in order to develop new diagnostic and treatment technologies.As a society, we need more knowledge about the correlation between e.g. inflammation and development of cancer, about biomarkers and about molecular mechanisms of autoimmunity in e.g. rheumatological conditions - not to mention chronic mucosal inflammation. In the inflammation network we collaborate interdisciplinarily in order to find answers.