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Department of Biomedicine

Human Immunology of Infectious Diseases

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Christensen, M. H., Jensen, S. B., Miettinen, J. J., Luecke, S., Prabakaran, T., Reinert, L. S., Mettenleiter, T., Chen, Z. J., Knipe, D. M., Sandri-Goldin, R. M., Enquist, L. W., Hartmann, R., Mogensen, T. H., Rice, S. A., Nyman, T. A., Matikainen, S. & Paludan, S. R. (2016). HSV-1 ICP27 targets the TBK1-activated STING signalsome to inhibit virus-induced type I IFN expression. EMBO Journal, 35(13), 1385-1399. https://doi.org/10.15252/embj.201593458, https://doi.org/10.15252/embj.201593458

Chiliveru, S., Rahbek, S. H., Jensen, S. K., Jørgensen, S. E., Nissen, S. K., Christiansen, S. H., Mogensen, T. H., Jakobsen, M. R., Iversen, L., Johansen, C. & Paludan, S. R. (2014). Inflammatory Cytokines Break Down Intrinsic Immunological Tolerance of Human Primary Keratinocytes to Cytosolic DNA. Journal of Immunology. https://doi.org/10.4049/jimmunol.1302120

Chan, Y. H., Liu, Z., Bastard, P., Khobrekar, N., Hutchison, K. M., Yamazaki, Y., Fan, Q., Matuozzo, D., Harschnitz, O., Kerrouche, N., Nakajima, K., Amin, P., Yatim, A., Rinchai, D., Chen, J., Zhang, P., Ciceri, G., Chen, J., Dobbs, K. ... Zhang, S. Y. (2024). Human TMEFF1 is a restriction factor for herpes simplex virus in the brain. Nature, 632(8024), 390-400. https://doi.org/10.1038/s41586-024-07745-x

COVID Human Genetic Effort (2024). SARS-CoV-2 brainstem encephalitis in human inherited DBR1 deficiency. Journal of Experimental Medicine, 221(9), Article e20231725. https://doi.org/10.1084/jem.20231725

Cham, L. B., Whitehead, B., Werner, M., Jensen, F., Zippor, M., Mogensen, T. H., Netea, M. G., Williams, A. R. & Nejsum, P. (2025). Helminth infection induces innate immune priming in plasmacytoid dendritic cells. The Journal of Infectious Diseases, 232(1), 230-235. https://doi.org/10.1093/infdis/jiaf009

Casanova, J. L., Su, H. C. & COVID Human Genetic Effort (2020). A Global Effort to Define the Human Genetics of Protective Immunity to SARS-CoV-2 Infection. Cell, 181(6), 1194-1199. https://doi.org/10.1016/j.cell.2020.05.016

Carter-Timofte, M. E., Hansen, A. F., Christiansen, M., Paludan, S. R. & Mogensen, T. H. (2019). Mutations in RNA Polymerase III genes and defective DNA sensing in adults with varicella-zoster virus CNS infection. Genes and Immunity, 20(3), 214-223. https://doi.org/10.1038/s41435-018-0027-y

Carter-Timofte, M. E., Hansen, A. F., Mardahl, M., Fribourg, S., Rapaport, F., Zhang, S.-Y., Casanova, J.-L., Paludan, S. R., Christiansen, M., Larsen, C. S. & Mogensen, T. H. (2018). Varicella-zoster virus CNS vasculitis and RNA polymerase III gene mutation in identical twins. Neurology: Neuroimmunology & Neuroinflammation, 5(6), e500. https://doi.org/10.1212/NXI.0000000000000500

Carter-Timofte, M. E., Paludan, S. R. & Mogensen, T. H. (2018). RNA Polymerase III as a Gatekeeper to Prevent Severe VZV Infections. Trends in Molecular Medicine, 24(10), 904-915. https://doi.org/10.1016/j.molmed.2018.07.009

Carter-Timofte, M. E., Jørgensen, S. E., Freytag, M. R., Thomsen, M. M., Brinck Andersen, N. S., Al-Mousawi, A., Hait, A. S. & Mogensen, T. H. (2020). Deciphering the Role of Host Genetics in Susceptibility to Severe COVID-19. Frontiers in Immunology, 11, Article 1606. https://doi.org/10.3389/fimmu.2020.01606

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Marcus Høy Hansen