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Department of Biomedicine

Human Immunology of Infectious Diseases

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Mogensen, T. H. (2022). Unexplored roles of type I interferon in antiviral immunity and regulation of inflammation revealed by studying patients with inborn errors of immunity. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 74(1), 140–143. https://doi.org/10.1093/cid/ciaa1798

Bastard, P., Gervais, A., Le Voyer, T., Rosain, J., Philippot, Q., Manry, J., Michailidis, E., Hoffmann, H. H., Eto, S., Garcia-Prat, M., Bizien, L., Parra-Martínez, A., Yang, R., Haljasmägi, L., Migaud, M., Särekannu, K., Maslovskaja, J., Prost, N. D., Tandjaoui-Lambiotte, Y. ... Imagine COVID Group (2021). Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths. Science Immunology, 6(62), Article 4340. https://doi.org/10.1126/sciimmunol.abl4340

Reinert, L. S., Rashidi, A. S., Tran, D. N., Katzilieris-Petras, G., Hvidt, A. K., Gohr, M., Fruhwürth, S., Bodda, C., Thomsen, M. K., Vendelbo, M. H., Khan, A. R., Hansen, B., Bergström, P., Agholme, L., Mogensen, T. H., Christensen, M. H., Nyengaard, J. R., Sen, G. C., Zetterberg, H. ... Paludan, S. R. (2021). Brain immune cells undergo cGAS/STING-dependent apoptosis during herpes simplex virus type 1 infection to limit type I IFN production. Journal of Clinical Investigation, 131(1), Article e136824. https://doi.org/10.1172/JCI136824

Paludan, S. R. & Mogensen, T. H. (2021). Constitutive and latent immune mechanisms exert ‘silent’ control of virus infections in the central nervous system. Current Opinion in Immunology, 72, 158-166. https://doi.org/10.1016/j.coi.2021.05.004

Paludan, S. R., Pradeu, T., Masters, S. L. & Mogensen, T. H. (2021). Constitutive immune mechanisms: mediators of host defence and immune regulation. Nature Reviews Immunology, 21(3), 137-150. https://doi.org/10.1038/s41577-020-0391-5

Hait, A. S., Olagnier, D., Sancho-Shimizu, V., Skipper, K. A., Helleberg, M., Larsen, S. M., Bodda, C., Moldovan, L. I., Ren, F., Brinck Andersen, N.-S., Thomsen, M. M., Freytag, M. R., Darmalinggam, S., Parkes, I., Kadekar, D. D., Rahbek, S. H., van der Horst, D., Kristensen, L. S., Eriksson, K. ... Mogensen, T. H. (2021). Defects in LC3B2 and ATG4A underlie HSV2 meningitis and reveal a critical role for autophagy in antiviral defense in humans. Science Immunology, 5(54), Article eabc2691. https://doi.org/10.1126/sciimmunol.abc2691

Brinck Andersen, N. S., Jørgensen, S. E., Skipper, K. A., Larsen, S. M., Heinz, J., Thomsen, M. M., Farahani, E., Cai, Y., Hait, A. S., Kay, L., Giehm Mikkelsen, J., Høgsbjerg Schleimann, M., Thomsen, M. K., Paludan, S. R. & Mogensen, T. H. (2021). Essential role of autophagy in restricting poliovirus infection revealed by identification of an ATG7 defect in a poliomyelitis patient. Autophagy, 17(9), 2449-2464. https://doi.org/10.1080/15548627.2020.1831800

Arkin, L. M., Moon, J. J., Tran, J. M., Asgari, S., O'Farrelly, C., Casanova, J. L., Cowen, E. W., Mays, J. W., Singh, A. M., Drolet, B. A. & COVID Human Genetic Effort (2021). From Your Nose to Your Toes: A Review of Severe Acute Respiratory Syndrome Coronavirus 2 Pandemic‒Associated Pernio. Journal of Investigative Dermatology, 141(12), 2791-2796. https://doi.org/10.1016/j.jid.2021.05.024

Katzenstein, T. L., Jørgensen, S. E., Mortensen, J., Helleberg, M., Kalhauge, A. & Mogensen, T. H. (2021). Fulminant H1N1 and severe acute respiratory syndrome coronavirus-2 infections with a 4-year interval without an identifiable underlying cause: a case report. Journal of Medical Case Reports, 15(1), Article 505. https://doi.org/10.1186/s13256-021-03113-9

Thomsen, M. M., Tyrberg, T., Skaalum, K., Carter-Timofte, M., Freytag, M. R., Norberg, P., Helleberg, M., Storgaard, M., Nielsen, H., Bodilsen, J., Grahn, A. & Mogensen, T. (2021). Genetic variants and immune responses in a cohort of patients with varicella zoster virus encephalitis. The Journal of Infectious Diseases, 224(12), 2122-2132. https://doi.org/10.1093/infdis/jiab254

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Marcus Høy Hansen