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Department of Biomedicine

Human Immunology of Infectious Diseases

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Al Qureshah, F., Le Pen, J., de Weerd, N. A., Moncada-Velez, M., Materna, M., Lin, D., Milisavljevic, B., Vianna, F., Bizien, L., Lorenzo, L., Lecuit, M., Pommier, J. D., Keles, S., Ozcelik, T., Pedraza-Sanchez, S., de Prost, N., El Zein, L., Hammoud, H., F P Ng, L. ... Durand, B. (2025). A common form of dominant human IFNAR1 deficiency impairs IFN-α and -ω but not IFN-β-dependent immunity. Journal of Experimental Medicine, 222(2), Article e20241413. Advance online publication. https://doi.org/10.1084/jem.20241413

Bak, R. O., Holm, M., Møller, B., Mikkelsen, J. G. & Mogensen, T. H. (2025). CRISPR/Cas-geneditering af humane stamceller til kurativ behandling af primær immundefekt. Ugeskrift for Læger, 187(22), 1-7. https://doi.org/10.61409/V02250083

Hinke, D. M., Dorset, S. R., Bratland, E., Wolff, J. H., Olsnes, A. M., Mikkelsen, J. G., Helgeland, L., Bak, R. O., Benneche, A. & Mogensen, T. H. (2025). CXCR2 deficiency with myelokathexis caused by a novel variant: correction via CRISPR/Cas9. Haematologica, 111(2), 738-744. https://doi.org/10.3324/haematol.2025.288111

Hu, L., van der Sluis, R. M., Castelino, K. B., Zhang, B.-C., Ronit, A., Zillinger, T., Werner, M., Jørgensen, S. E., Hansen, A. L., Pedersen, A., Narita, R., Reinert, L. S., Bundgaard, B., Holm, C. K., Cobat, A., Casanova, J.-L., Reggiori, F., Mari, M., Paludan, S. R. ... COVID Human Genetic Effort (2025). Deleterious variants in the autophagy-related gene RB1CC1/FIP200 impair immunity to SARS-CoV-2. Nature Communications, 16(1), Article 10618. https://doi.org/10.1038/s41467-025-65308-8

van der Sluis, R. M., García-Rodríguez, J. L., Nielsen, I. H., Gris-Oliver, A., Becker, J., Costa, B., Chaudhry, M. Z., Werner, M., Laustsen, A., Pedersen, J. G., Gammelgaard, K. R., Mogensen, T. H., Kalinke, U., Cicin-Sain, L., Bak, R. O., Kristensen, L. S. & Jakobsen, M. R. (2025). Distinctive CD8⁺ T cell activation by antigen-presenting plasmacytoid dendritic cells compared to conventional dendritic cells. Cell Reports, 44(3), Article 115413. https://doi.org/10.1016/j.celrep.2025.115413

Hansen, K. S., Jørgensen, S. E., Cömert, C., Schiøttz-Christensen, B., Bross, P., Agergaard, J., Leth, S., Østergaard, L., Palmfeldt, J., Olsen, R. K. J. & Mogensen, T. H. (2025). Genetic Landscape and Mitochondrial Metabolic Dysregulation in Patients Suffering From Severe Long COVID. Journal of Medical Virology, 97(3), Article e70275. https://doi.org/10.1002/jmv.70275

Cham, L. B., Whitehead, B., Werner, M., Jensen, F., Zippor, M., Mogensen, T. H., Netea, M. G., Williams, A. R. & Nejsum, P. (2025). Helminth infection induces innate immune priming in plasmacytoid dendritic cells. The Journal of Infectious Diseases, 232(1), 230-235. https://doi.org/10.1093/infdis/jiaf009

Girault, V., Stukalov, A., Carter-Timofte, M. E., Hertzog, J., Verin, M., Austen, K., Haas, D. A., Oubraham, L., Piras, A., Maidl, S., Öllinger, R., Rad, R., Protzer, U., Kaufer, B. B., Lebbink, R. J., Rehwinkel, J., Mogensen, T. H. & Pichlmair, A. (2025). Multi-proteomic profiling of the varicella-zoster virus–host interface reveals host susceptibilities to severe infection. Nature Microbiology, 10(8), 2048-2072. https://doi.org/10.1038/s41564-025-02068-7

Herlin, L. K., Schmidt, S. A. J., Mogensen, T. H. & Sommerlund, M. (2025). Risk of Death, Infections, and Hyperthermia in Ectodermal Dysplasias: A Nationwide Study. Acta Dermato-Venereologica, 105, Article adv43101. https://doi.org/10.2340/actadv.v105.43101

Zhang, B.-C., Pedersen, A., Reinert, L. S., Li, Y., Narita, R., Idorn, M., Hu, L., Skouboe, M. K., Li, S., Maimaitili, M., Ding, X., Cong, Y., Zhao, J., Frémond, M.-L., Mikkelsen, K., Gao, Z., Huang, J.-R., Thomsen, E. A., Mikkelsen, J. H. ... Paludan, S. R. (2025). STING signals to NF-κB from late endolysosomal compartments using IRF3 as an adaptor. Nature Immunology, 26(11), 1916-1930. https://doi.org/10.1038/s41590-025-02283-8

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Marcus Høy Hansen