Marie Louise Næstholt Dahl

Title

PhD Student, Dr

Primary affiliation

Marie Louise Næstholt Dahl

Areas of expertise

  • Autoimmunity
  • Autoantibodies
  • Rheumatology
  • Sjögren's Syndrome
  • Autoantibody-protein interactions

Contact information

Email address

Profile

As a Ph.D. student in Bent Deleuran's lab, I conduct research on autoimmune diseases within the field of rheumatology. In our group, we are interested in autoantibodies and their role in disease development, and we conduct both basic and translational research. As an MD specializing in rheumatology, I possess a unique insight and perspective on patients and diseases, enabling me to pose research questions with tangible clinical impact.

Research

My Ph.D. project focuses on the autoantibody anti-Ro52, which targets the intracellular FC receptor TRIM21. During my time at the Department of Biomedicine, I have worked on:

1) Understanding why these autoantibodies are produced.

2) Exploring their potential use in disease prediction, and 

3) Investigating how they alter normal physiology into the disease-specific traits we observe in our patients. 

Teaching activities

I teach medical and molecular medicine students immunology, rheumatology, internal medicine, and acute medicine, with a focus on using the basic sciences to better understand the clinical world. 

Collaborations

I collaborate with rheumatologists, clinical immunologists, hepatologists, and other clinicians both nationally and internationally to answer research questions about autoimmune diseases. Most recently, I had a research stay with Leo James at the MRC Lab of Molecular Biology in Cambridge, focusing on how anti-Ro52 autoantibodies alter TRIM21 function. 

Selected publications

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