Telemetry and blood pressure measurements

Accurate and reliable blood pressure measurement can be essential for understanding the physiology and pathology of cardiovascular disease. We offer both non-invasive (traditional sphygmomanometers) and invasive (telemetry) methods.

Need help?

Send an email to phenotyping@biomed.au.dk 

and we will get back to you as soon as possible.


Telemetry

Applications in brief

Telemetry allows in situ collection of various data types from an implanted cordless transmitter without restraint or handling of the animals. The type of collected data depends on the implant type, making telemetry a relevant tool for e.g. behavioural, sleep and pain studies.

Features

Transmitters can be implanted subcutaneously or intraperitoneally. Implants normally have a main feature, but are often not limited to these measurements.

For data collection including:

  • blood pressure
  • ventricle pressure
  • bladder pressurec
  • cranial pressure
  • biopotentials (ECG, EEG, EMG or EOG)
  • movement
  • temperature
  • respiration
  • glucose concentration (e.g. for metabolic and diabetes studies)

Which species may I investigate?

  • Telemetry implants are available for mice (up to 24 simultaneous measurements possible).
  • Telemetry implants are also available for rats.

Location

Telemetry equipment is located in the Skou building animal facility. Therefore, please familiarize yourself with guidelines and regulations regarding animals as well as user quarantine regulations.

Pricing

Telemetry equipment is available for rental, and fees are given per animal for the duration of the rental period. Prices include surgery and data collection. In case of advanced data analysis and interpretation, please contact us on phenotyping@biomed.au.dk - we are happy to help!

Tips and Tricks

More information on telemetry in behavioral, sleep and pain studies.

Specifications

PA-C10 transmitter
Data type

Data type depends on implantation site

systolic, diastolic and mean pressure, as well as BPM, animal activity and respiratory rate (arterial implantation site)

left ventricular pressure

bladder pressure

intra-cranial pressure

Animal size > 17 g
Battery life 4-6 weeks
Resusable yes
HD-X11 transmitter
Data type

Features in addition

  • temperature
  • biopotentials (ECG, EEG, EMG or EOG)
Animal size > 19 g
Battery life 4-6 weeks
Resusable yes

Tail-cuff for non-invasive blood pressure measurements

Applications in brief

With the Coda4 Tail-cuff system, blood pressure can be measured in up to 4 restrained, alert mice.

Features

With an inflatable tail-cuff, the blood flow in the tail is temporarily occluded, and systolic and diastolic pressures are registered as air is released from the tail-cuff, allowing blood flow to return to the tail. Animals should be trained for the procedure to avoid stress.

Location

Telemetry equipment is located in the Skou building animal facility. Therefore, please familiarize yourself with guidelines and regulations regarding animals as well as user quarantine regulations.

Tips and Tricks

Should I perform training sessions?

Animals should be trained for the procedure to avoid stress.