Osmotic pumps allow continuous compound administration, without repeated injection or handling of animals. Osmotic pumps are inserted subcutaneously (anesthesia required) in the scapular region or intraperitoneally, depending on animal and osmotic pump size. Osmotic pumps are preloaded with the wanted compound or solution, with doses according to animal size. The concentration of the solution needs to be calculated from the pump’s fixed dose/delivery rate and total duration of administration, for the desired final dose to be correct. The pump size determines the loading volume and duration of administration.

Osmotic pumps can be implanted subcutaneously in the scapular region or intraperitoneally.

• continuous compound administration
• accurate compound administration
• animal stress reduction from repeated injections and handling

Solutions compatible with Alzet osmotic pumps

• aqueous solutions
• dilute acids and bases
• dilute/low concentrations of DMSO and ethanol

• mice
• rats
• contact us on phenotyping@biomed.au.dk for osmotic pumps for other species

If osmotic pump procedures are performed in the Skou building animal facility, please familiarize yourself with guidelines and regulations regarding animals as well as user quarantine regulations.

• The researcher has to supply osmotic pumps and the compound/solution to be administered.
• Do not hesitate to contact us on phenotyping@biomed.au.dk for guidance on dosing and choice of osmotic pump - we are happy to help!

Instech vascular access buttons (VABs^TM) allow for repeated injections or sampling. The button is insered subcutaneously and connected to one or more catheters that are inserted into the wanted vessel(s). The button and aluminimum cap ensure a closed system, preventing evaporation, improving patency, and allowing aseptic conditions. The cap is magnetic and stays in place so that animals can be co-housed. The button connects to PinPorts, which have standard luer connectors. Implantation requires anesthesia, but sampling can be done on alert animals afterwards.

Vascular access buttons are implanted subcutaneously for

• repeated compound administration
• repeated sampling
• accurate compound administration
• accurate sampling
• animal stress reduction from repeated injections and handling; Instech ascular access buttons are part of the Be Nice products, developed with the 3Rs in mind

• mice
• rats
• contact us on phenotyping@biomed.au.dk for vascular access buttons for other species

If vascular access button procedures are performed in the Skou building animal facility, please familiarize yourself with guidelines and regulations regarding animals as well as user quarantine regulations.

• The researcher has to supply vascular access buttons and the compound/solution to be administered.
• Do not hesitate to contact us on phenotyping@biomed.au.dk for guidance on dosing and choice of vascular access button - we are happy to help!