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Department of Biomedicine

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Hollensen, A. K., Thomsen, R., Bak, R. O., Petersen, C. C., Ermegaard, E. R., Aagaard, L., Damgaard, C. K. & Mikkelsen, J. G. (2017). Improved microRNA suppression by WPRE-linked Tough Decoy microRNA sponges. RNA, 23(8), 1247-1258. https://doi.org/10.1261/rna.061192.117

Holm, R., Khandelwal, J., Einholm, A. P., Andersen, J. P., Artigas, P. & Vilsen, B. (2017). Arginine substitution of a cysteine in transmembrane helix M8 converts Na+,K+-ATPase to an electroneutral pump similar to H+,K+-ATPase. Proceedings of the National Academy of Sciences (PNAS), 114(2), 316-321.

Holm, K., Collin, M., Kristensen, L. H., Jensen, A. & Rasmussen, M. (2017). Three variants of the leukotoxin gene in human isolates of Fusobacterium necrophorum subspecies funduliforme. Anaerobe, 45, 129-132. https://doi.org/10.1016/j.anaerobe.2017.03.016

Holmgaard, A., Askou, A. L., Benckendorff, J. N. E., Thomsen, E. A., Cai, Y., Bek, T., Mikkelsen, J. G. & Corydon, T. J. (2017). In Vivo Knockout of the Vegfa Gene by Lentiviral Delivery of CRISPR/Cas9 in Mouse Retinal Pigment Epithelium Cells. Molecular Therapy - Nucleic Acids, 9, 89-99. https://doi.org/10.1016/j.omtn.2017.08.016

Hostrup, M., Jessen, S., Onslev, J., Clausen, T. & Porsbjerg, C. (2017). Two-week inhalation of budesonide increases muscle Na,K ATPase content but not endurance in response to terbutaline in men. Scandinavian Journal of Medicine & Science in Sports, 27(7), 684-691. https://doi.org/10.1111/sms.12677

Hussmann, D., Madsen, A. T., Jakobsen, K. R., Luo, Y., Sorensen, B. S. & Nielsen, A. L. (2017). IGF1R depletion facilitates MET-amplification as mechanism of acquired resistance to erlotinib in HCC827 NSCLC cells. OncoTarget, 8(20), 33300-33315. https://doi.org/10.18632/oncotarget.16350

Hvam, M. L., Cai, Y., Dagnæs-Hansen, F., Nielsen, J., Wengel, J., Kjems, J. & Howard, K. (2017). Fatty acid-modified gapmer antisense oligonucleotide and human serum albumin constructs for pharmacokinetic modulation. Molecular Therapy, 25(7), 1710-1717. https://doi.org/10.1016/j.ymthe.2017.05.009

Inui, K., Zhao, Z., Yuan, J., Jayaprakash, S., Le, L. T. M., Drakulic, S., Sander, B. & Golas, M. M. (2017). Stepwise assembly of functional C-terminal REST/NRSF transcriptional repressor complexes as a drug target. Protein Science, 26(5), 997-1011. https://doi.org/10.1002/pro.3142

Isaksen, T. J., Kros, L., Vedovato, N., Holm, T. H., Vitenzon, A., Gadsby, D., Khodakhah, K. & Lykke-Hartmann, K. (2017). Hypothermia-induced dystonia and abnormal cerebellar activity in a mouse model with a single disease-mutation in the sodium-potassium pump. PLOS Genetics, 13(5), Article e1006763. https://doi.org/10.1371/journal.pgen.1006763

Jakobsen, K. R., Demuth, C., Tranberg Madsen, A., Hussmann, D., Vad-Nielsen, J., Nielsen, A. L. & Sørensen, B. S. (2017). MET amplification and epithelial-to-mesenchymal transition exist as parallel resistance mechanisms in erlotinib-resistant, EGFR-mutated, NSCLC HCC827 cells. Oncogenesis, 6(4), e307. Article e307. https://doi.org/10.1038/oncsis.2017.17

Jang, K. S., Nyegaard, M., Neidleman, J., Chen, J., Spitzer, T., Vo, K. C., Greene, W. C., Giudice, L. & Roan, N. R. (2017). IL11, a key cytokine for implantation, is potently induced by microvesicles from human seminal plasma.

Januliene, D., Andersen, J. L., Nielsen, J. A., Quistgaard, E. M., Hansen, M., Strandbygaard, D., Moeller, A., Petersen, C. M., Madsen, P. & Thirup, S. S. (2017). Acidic Environment Induces Dimerization and Ligand Binding Site Collapse in the Vps10p Domain of Sortilin. Structure, 25(12), 1809-1819.e3. Article 12. https://doi.org/10.1016/j.str.2017.09.015

Januliene, D., Manavalan, A., Ovesen, P. L., Pedersen, K. M., Thirup, S., Nykjær, A. & Moeller, A. (2017). Hidden Twins: SorCS Neuroreceptors Form Stable Dimers. Journal of Molecular Biology, 429(19), 2907-2917. https://doi.org/10.1016/j.jmb.2017.08.006

Jendroszek, A., Sønnichsen, M., Chana Munoz, A., Leyman, K., Christensen, A., Petersen, S. V., Bendixen, C., Panitz, F., Andreasen, P. & Jensen, J. K. (2017). Latency transition of plasminogen activator inhibitor type 1 is evolutionarily conserved. Thrombosis and Haemostasis, 117(9), 1688-1699. https://doi.org/10.1160/TH17-02-0102

Jensen, R. K., Pihl, R., Laursen, N. S., Thiel, S. & Andersen, G. R. (2017). A novel nanobody inhibitor of the alternative pathway. Molecular Immunology, 89, 198. https://doi.org/10.1016/j.molimm.2017.06.207

Jensen, J. M., Villesen, P., Friborg, R. M., Mailund, T., Besenbacher, S., Schierup, M. H. & Danish Pan-Genome Consortium (Jakob Grove, member of -) (2017). Assembly and analysis of 100 full MHC haplotypes from the Danish population. Genome Research, 27(9), 1597-1607. https://doi.org/10.1101/gr.218891.116

Jensen, D. K., Villumsen, A., Skytte, A.-B., Madsen, M. G., Sommerlund, M. & Bendstrup, E. (2017). Birt-Hogg-Dubé syndrome: a case report and a review of the literature. European Clinical Respiratory Journal, 4(1), Article 1292378. https://doi.org/10.1080/20018525.2017.1292378

Jensen, K. T., Fløe, L., Petersen, T. S., Huang, J., Xu, F., Bolund, L., Luo, Y. & Lin, L. (2017). Chromatin accessibility and guide sequence secondary structure affect CRISPR-Cas9 gene editing efficiency. FEBS Letters, 591(13), 1892-1901. https://doi.org/10.1002/1873-3468.12707

Jensen, I. S., Inui, K., Drakulic, S., Jayaprakash, S., Sander, B. & Golas, M. M. (2017). Expression of Flp Protein in a Baculovirus/Insect Cell System for Biotechnological Applications. Protein Journal, 36(4), 332-342. https://doi.org/10.1007/s10930-017-9724-z

Jensen, A., Stausbøl-Grøn, B., Riber-Hansen, R. & d'Amore, F. (2017). Ibrutinib-Associated Skin Toxicity: A Case of Maculopapular Rash in a 79-Year Old Caucasian Male Patient with Relapsed Waldenstrom's Macroglobulinemia and Review of the Literature. Dermatology Reports, 9(1), 6976. https://doi.org/10.4081/dr.2017.6976

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