How do acid-base derangements and metabolic disturbances influence cell functions, and can these mechanisms be manipulated for the benefit of patients?
How are thousands to billions of cells produced and arranged in space and time to execute a defined task at the cell level and cooperatively achieve a biological outcome at the organ level?
How can we improve treatment for patients suffering from water balance disorders or intestinal dysfunction caused by excess bile acids in the large intestine?
How is cerebrospinal fluid produced and does the composition of the fluid have an influence on other functions in the brain?
Which attack molecules use bacteria to penetrate the body during severe and life-threatening urinary tract infections which have spread to the kidneys?
How can we clarify cellular mechanisms and use the knowledge to treat certain eye- and kidney diseases?
The molecular origins and pathways associated with the development and progression of human cardiac and skeletal myopathies.
What role do the small blood vessels play in serious neurological disorders?