The fifth meeting of the Danish Single-Cell community takes place at the University of Copenhagen. It is a two-day event combining the annual meetings of the Danish Single-Cell Network and the CellX (Danish Single Cell Examination Platform). 

Join us for an exciting program exploring cutting-edge topics in single-cell research featuring nationally and internationally renowned speakers. The event offers opportunities to showcase your work during poster sessions, connect with colleagues and collaborators, and engage with exhibitors presenting the latest tools and technologies. Don’t miss this chance to expand your knowledge and network within the single-cell research community!

Check out CellX LinkedIn for symposium's post-event coverage. 

Programme

5th Danish Single-Cell Symposium: Technology Towards Cell Biology and Medicine

15-May-2025

08:00 - 09:00 Registration and coffee

Pick up your name tag, mount your poster, and/or grab a cup of coffee and light breakfast

09:00 - 9:30 Welcome

Welcome to symposium and organizational information - Konstantin Khodosevich

Presentation of the Danish Single Cell Network - Tune Pers

CellX introduction, overview and update - Søren Riis Paludan

9:30 - 12:20 Session I - Biotechnology and Single-Cell wet-lab applications

Chair: Konstantin Khodosevich, KU

9:30 – 10:10 Invited talk

Marek Bartosovic

University of Stockholm, Sweden

"Deciphering the epigenetic landscape of the brain: Innovations in chromatin profiling with single-cell and spatial nano-CUT&Tag"

10:10 – 10:50 Invited talk

Laura Hinte

ETH Zurich, Switzerland

“Cellular Remodeling of Human Adipose Tissue in Obesity and Weight Loss”

10:50 – 11:10 Short break

11:10 – 11:40 Invited local speaker

Anne Loft

University of Southern Denmark

"Single-Cell Dissection of Adipose Tissue Plasticity in Obesity and Beyond"

11:40 – 11:50 Company Pitch # 1

Element Biosciences

11:50 – 12:00 Company Pitch # 2

BioNordika (Cell Signaling Technology)

12:00 – 12:10 Company Pitch # 3

Akoya Biosciences

12:10 – 12:20 Company Pitch # 4

Illumina

12:20 - 14:00 Lunch break and sponsor exhibition

Exhibition Area

Session II – Proteomics in Single-Cell studies

Chairs: Lei Cheng, AU ; Ermelinda Porpiglia, AU

14:00 – 14:40 Invited talk

Karl Mechtler

Vienna BioCenter, IMP, Austria

"Challenging the Astral mass analyzer to quantify up to 5,300 proteins per single cell at unseen accuracy to uncover cellular heterogeneity"

14:40 – 15:10 Invited local Speaker

Erwin Schoof

Technical University of Denmark

"Using single-cell proteomics by MS to disentangle complex cellular hierarchies"

15:10 – 15:30 Coffee break

15:30 – 16:00 Invited local Speaker

Ermelinda Porpiglia

Aarhus University

"Through the lens of CyTOF: Mapping niche dynamics in skeletal muscle at single-cell resolution"

Short talk session I

16:00 – 16:15 Short Talk #1

Frederik Nørby Friis Sørensen

Copenhagen University

" Cortical tubers in tuberous sclerosis complex shows molecular structure preservation, altered AMPA receptor signaling and massive reorganization of metabolism"

16:15 – 16:30 Short Talk #2

Shobana Stassen

University of Hong Kong

" StaVia: spatially and temporally aware cartography with higher-order random walks for single cell atlases"

16:30 – 16:45 Short Talk #3

Tu Hu

Statens Serum Institut

" Autonomous AI Agents for Single-cell RNA-seq Data: Beyond Data Processing Toward Contextualized Interpretation"

16:45 – 17:00 Short Talk #4

Julius Elliot Raagaard Grothen

Novo Nordisk

" Using single-nucleus RNA-sequencing to access skeletal muscle adaptations to exercise"

Poster session and dinner buffet

Poster session starts at 18:00 and dinner is served from 18:30 while the poster session

continues. Feel free to bring your dinner around with you as you visit the posters and

exhibitors.

16-May-2025

08:30 - 09:00 Arrival and Morning coffee

Grab a croissant or some fruit and a cup of coffee to start your 2nd day at the symposium

09:00 - 12:00 Session III - Bioimaging and applications in single-cell technologies

Chair: Jonathan Brewer, SDU

9:00 – 9:40 Invited talk

Paulo Cadinu

Harvard Medical School, US

"Inflammatory Bowel Disorder under the lens of genomic microscopy"

9:40 – 10:20 Invited talk

Nigel B. Jamieson

University of Glasgow, UK

"Spatial-omic characterisation of Colorectal Cancer"

10:20 – 10:40 Short break

10:40 – 11:10 Invited local Speaker

Richard Röttger

University of Southern Denmark

"Benchmarking Spatial Transcriptomics Simulation Methods using Cellular Neighborhoods"

Short talk session II

11:10 – 11:25 Short Talk #5

Bernd Coester

University of Copenhagen

" Getting the bigger picture: Generation of a spatially resolved projectome of the hypothalamus"

11:25 – 11:40 Short Talk #6

El Mehdi Baknine

Statens Serum Institut

" Single-Cell Transcriptomic Profiling of M. tuberculosis-infected Lungs Reveals Immune Dynamics Following H107e/CAF Vaccination Against Tuberculosis in Mice"

11:40 – 11:55 Short Talk #7

Giacomo Schmidt Frattari

Aarhus University Hospital

"Bridging Assays with Single-Cell TCR Sequencing to Dissect Cytotoxic CD4+ T Cells in HIV-1 Control"

12:00 - 14:00 Lunch break and sponsors exhibition

14:00 - 16:00 Session IV – Epigenomics and gene regulation

Chair: Tune H Pers, KU

14:00 – 14:40 Invited talk

Georgios Kalamakis

ETH Zurich, Switzerland

"CRISPR Screens in Vivo: Uncovering Liver Fibrosis Modulators"

14:40 – 15:10 Invited local Speaker

Kyung Min Noh

Aarhus University

"Functional dissection of the disease-associated chromatin regulators using CRISPRi and single-cell multiomics"

15:10 – 15:30 Short break

15:30 – 16:00 Invited local Speaker

Robin Andersson

University of Copenhagen

"Mapping enhancer-gene regulatory interactions from single-cell data"

16:00 - 16:15 Closing remarks

Announcing the short-talk and poster awards. Closing remarks from event organizers.