Rooms and equipment

Researchers in The Animal Facility have different equipment and customized rooms at their disposal. Below you can read more about what is available, where to find it and who to contact if you are interested in using the equipment and/or rooms.

Behavior room, mouse (1115-017)

The largest behavior room for mice is located on the ground floor in The Animal Facility. It consists of a large front room (1115-017 Prep room behavior) for preparing experiments, setting up software and video monitoring and storing equipemt for behavior experiments as well as two separate back rooms (1115-017 Behavior (right) and 1115-017 Behavior (left)) where the the actual experiments can be performed. In room 1115-017 (right) a camera is mounted in the ceiling for recording of behavior. The rooms can be booked in Outlook, if in doubt, please see the booking guide to the right.

The storage space in the room is shared, and equipment inside the behavior room as well as on the shelves outside the room belongs to different research groups. If you want to borrow equipment (e.g. rotarod, open field arena, elevated plus maze etc.) please check who owns the equipment and talk to the relevant lab manager or book in the physical calendars placed next to the equipment in the room or on the shelves.

Contact

The rooms are maintained and managed by The Animal Facility. If you have questions for booking or resources in the room, please contact the veterinarians at vet.biomed@biomed.au.dk.

Behavior room, mouse (1115-K23B)

This smaller behavior room consists of a front room (1115-K23B) for preparing animals for experiments, storing equipment etc. as well as two separate back rooms (1115-K23C and 1115-K23D) where the the actual experiments can be performed. In room 1115-K23x a camera is mounted in the ceiling for recording of behavior. The rooms can be booked in Outlook, if in doubt, please see the booking guide to the right.

Contact

The rooms are maintained and managed by The Animal Facility. If you have questions for booking or resources in the room, please contact the veterinarians at vet.biomed@biomed.au.dk.

Class 2 laboratory, mouse (1115-K18B)

In 1115-K18B there is a small class 2 laboratory where experimental work with class 2 biological agents can be performed in mice. The mice can be housed temporarily in single-use cages in the room, if necessary. The room contains a fume hood and a LAF bench and a regular work station.

Access to this room is restricted and will require an access card approved to enter this room. Access is granted upon completion of a physical introduction to the room which will include information on proper dress code and additional PPE required, use of and housing in single-use cages, handling and packing of waste, use of fume hood and anesthesia setup etc.For this room, special dress code applies and additional PPE is required when entering.

Contact

The class 2 laboratory is maintained and managed by The Animal Facility. If you have questions for booking or resources in the room, please contact the class 2 team Karina Lassen Holm (karinaholm@biomed.au.dk) and Kien Strand Olesen (kso@biomed.au.dk) or the veterinarians at vet.biomed@biomed.au.dk.

Class 2 and 3 laboratories, mouse/rat (1115-K30)

The large class 2 and 3 area consists of multiple different laboratories. Each lab is described in detail below and is entered through a common class 2 area containing a changing station. All animals are housed in IVCs throughout these laboratories. For all rooms, special dresscode applies and you have to wear additional PPE. Please ask in advance if you need special equipment for experiments in the rooms.

Access to these rooms are restricted and it will require an access card valid to enter the room. Access is granted upon completion of a physical introduction to the rooms which will include information on entry and exit procedure, proper dress code and additional PPE required, handling and packing of waste, use of changing station and LAF benches etc.

1115-K30C, Corona (mouse)

K30C is primarily used for research in coronavirus/COVID. The laboratory is equipped with a LAF bench as well as a downdraft table work station and a mobile anesthesia unit delivering Isoflurane.

1115-K30D, Class 3/Immune deficient (mouse)

K30D is used for housing serverly immune deficient mice like NOG, SCID or similar, or for performing experiments with class 3 biological agents requiring BSL3 laboratory circumstances. The laboratory is equipped with a LAF bench as well as a downdraft table work station and a mobile anesthesia unit delivering Isoflurane.

1115-K30E, Class 2 (mouse)

K30E is used for performing experiments with class 2 biological agents. The laboratory is equipped with a LAF bench, stereotaxic instruments as well as a downdraft table work station and a mobile anesthesia unit delivering Isoflurane.

1115-K30F, Class 2 (rat)

K30E is used for performing experiments with class 2 biological agents. The laboratory is equipped with a LAF bench, stereotaxic instruments as well as a downdraft table work station and a mobile anesthesia unit delivering Isoflurane.

Contact

The class 2 laboratories are maintained and managed by The Animal Facility. If you have questions for booking or resources in the rooms, please contact the class 2 team Karina Lassen Holm (karinaholm@biomed.au.dk) and Kien Strand Olesen (kso@biomed.au.dk) or the veterinarians at vet.biomed@biomed.au.dk.

EchoMRI (1115-K43B)

Whole Body Composition Analyser

The EchoMRI-100™ is a QMR system that measures whole body fat mass, lean tissue mass, free water, and total body water in live animals up to 100g, without the need for anesthesia or sedation. Typically, a scanning can be preformed in less than 1 minute. Because animals can be scanned alive, awake, and unrestrained the measurements are more comfortable and less stressful for both animals and their handlers. Animals can be scanned as frequently as needed without undue stress or other effects on their health and well-being. 

The equipment is placed in room 1115-K43B inside The Animal Facility in the Skou building at Department of Biomedicine, therefore it is only possible to scan animals from The Animal Facility at the moment. 

Contact

The equipment is managed by the Phenotyping Core Facility at Department of Biomedicine. Please refer to the Phenotyping Core Facility's website for specifications, training etc. The Phenotyping Core Facility can be contacted on phenotyping@biomed.au.dk.

Flex room, mouse/rat (1115-K21)

This flex room can be used for behavior experiments that do not require a lot of space or is not equipment heavy, or it can be used as an extra procedure room, for example if the regular procedure rooms are fully booked or for surgical procedures that require a quiet atmosphere or a minimum of disturbances. The room contains a downdraft table and has a point suction. If isoflurane anesthesia is to be used in the room, a mobile anesthesia unit must be booked and brought into the room.

The room is primarily to be used for mice, but can also be used for rats if the need arises.

Contact

The room is maintained and managed by The Animal Facility and can be booked in Outlook like other rooms and resources in the facility. If you have questions for booking or resources in the rooms, please contact the veterinarians at vet.biomed@biomed.au.dk.

Flex room, mouse/rat (1115-K23A)

This flex room can be used for behavior experiments that do not require a lot of space or is not equipment heavy, or it can be used as an extra procedure room, for example if the regular procedure rooms are fully booked or for surgical procedures that require a quiet atmosphere or a minimum of disturbances. The room contains a downdraft table and has a point suction. If isoflurane anesthesia is to be used in the room, a mobile anesthesia unit must be booked and brought into the room.

The room is primarily to be used for mice, but can also be used for rats if the need arises.

Contact

The room is maintained and managed by The Animal Facility and can be booked in Outlook like other rooms and resources in the facility. If you have questions for booking or resources in the rooms, please contact the veterinarians at vet.biomed@biomed.au.dk.

HM-2 cages, mouse (1115-K43D)

HM-2 Feed and Liquid Intake Monitoring

The HM-2 system is a food/water intake and activity monitor that can continuously monitor feeding and drinking activity in two independent channels (e.g. feed and drink) in group-housed rodents. The feeding and drinking data is collected without human intervention, it only requires identification of the individual animals with an RFID microchip. It is possible to record the start time of each meal, the amount of food consumed, the duration of the meal, and the finishing time as well as the circadian rhythm of the social group.

The equipment is placed in room 1115-K43D inside The Animal Facility in the Skou building at Department of Biomedicine, therefore it is only possible to perform monitoring on animals from The Animal Facility at the moment. 

Contact

The equipment is managed by the Phenotyping Core Facility at Department of Biomedicine. Please refer to the Phenotyping Core Facility's website for specifications, training etc. The Phenotyping Core Facility can be contacted on phenotyping@biomed.au.dk.

In Vivo Imaging System (1115-K18A)

Newton 7.0 Vilber

The in vivo imaging system enables researchers to quantify depth, geometry and intensity for both bioluminescent and fluorescent sources in three-dimensional spatial resolutions. The Newton 7.0 Vilber can be used for molecular and anatomical longitudinal studies of tumor, disease or inflammation development, visualization of cell trafficking and gene expression patterns and forming biodistribution and pharmacokinetic studies in live animals under anesthesia non-invasively. The system can be used for both rats and mice, or it can be used ex vivo for dissected organs of interest.

The equipment is placed in room 1115-K18A inside The Animal Facility in the Skou building at Department of Biomedicine, therefore it is only possible to scan animals from The Animal Facility at the moment. 

Contact

This imaging system is managed by the Bioimaging Core Facility at Department of Biomedicine. Please refer to the Bioimaging Core Facility's website for specifications, booking, training etc. and contact the Bioimaging Core Facility if you are interested in using the equipment.

The anesthesia required to image live animals is maintained and supported by The Animal Facility veterinarians. 

Irradiation room (1115-K36A)

Faxitron MultiRad 350

The MultiRad 350 is a 350 kV and 11,4 mA x-ray irradiation system that is fully shielded, self contained and that provides users with the ability to perform advanced irradiation techniques. It is designed to deliver the highest dose with the most uniform depth, and is ideal for very dense biological specimens and live animal irradiation. Whole body irradiation of mice takes place in pie cages on a motorized turntable for the most uniform dose delivery. The MultiRad 350 has a fully automated system geometry with programmable parameters such as field size, source to sample distance (SSD), filter selection, kV, mA and dose (Gy). Dose measurement control is done by monitoring entrance and exit dose while accounting for changes in system geometry. 

The equipment is placed in room 1115-K36A inside The Animal Facility in the Skou building at Department of Biomedicine, therefore it is only possible to irradiate animals from The Animal Facility at the moment.

If you want to know more, please reach out to the veterinarians to receive further specifications, or see the following in-house papers on comparing Cesium-137 with x-ray irradiation: 

Contact

The equipment is maintained and managed by The Animal Facility. The equipment is booked in Outlook and you can find a general booking guide to the right. If you have questions for booking or use of the equipment, please contact the veterinarians at vet.biomed@biomed.au.dk.

Metabolic cage room, mouse (1115-K51G)

The metabolic cage room is a temperature and humidity controlled room that can be used for housing mice in metabolic cages. The temperature and humidity is maintained at 28° Celcius and xx% relative humidity. The Animal Facility has a total of 42 complete metabolic cages that can be booked in Outlook. When booking, please remember the following:

  • Include full name (researcher/responsible) and number of mice to be included in the subject field of the booking
  • It is not allowed to make back-to-back bookings that will exceed the total number of metabolic cages as the service team in the animal facility need a minimum of 1-2 days to wash, clean and prepare cages for the next study/batch of mice

Contact

The metabolic cages and the room is maintained and managed by The Animal Facility. If you have questions to use of the room, cages, temperature or similar you can contact the Metabolic Cage Team consisting of Mads Thorling (mads.t@biomed.au.dk), Louise Østergaard Pedersen (lope@biomed.au.dk) and Martin Iburg Sølvstad (masoe@biomed.au.dk) or alternatively the veterinarians (vet.biomed@biomed.au.dk).

Micro-CT, mouse (1116-K42A)

Scanco VivaCT 80

The Scanco VivaCT 80 is an in-vivo micro Computed Tomography system. It enables scanning of animals such as mice and rats in vivo with an image resolution of up to 10.4 µm. This means that a bone microstructure may be followed over time to enable quantification of for example bone formed and removed during bone (re)modeling and the impact of growth, intervention, or disease in vivo. In addition, the scanner allows for scanning of soft tissue e.g. muscle either with or without use of contrast agents. Maximum scan dimeter is 80 mm and length is 145 mm. The scanner is controlled by an Open-VMS HP workstation, which is also used for short-time image storage. Image reconstruction is performed by an integrated GPU-based system.

The equipment is part of the Aarhus X-ray Image Alliance (AXIA) and placed in room 1116-K42A in The Animal Facility in the Skou building at Department of Biomedicine. Therefore it is only possible to scan animals from The Animal Facility at the moment.

Contact

If you want to know more about the equipment please refer to AXIA's website or contact Professor Annemarie Brüel (mb@biomed.au.dk) or Professor Jesper Skovhus Thomsen (jst@biomed.au.dk).

The anesthesia required to image live animals is maintained and supported by The Animal Facility veterinarians. 

Multiphoton/2-photon (1116-K42A)

Olympus FVMPE-RS

The 2-photon imaging system can be used for deep imaging in biological tissue. The system can be used for 3D imaging of tissue slices, organoids, whole organs, embryos, or live anesthetized animals. Efficient delivery and detection of photons in scattering media enable high signal-to-noise ratio acquisition, high sensitivity, and high-speed imaging to capture fast in vivo responses.

The equipment is placed in room 1116-K42A inside The Animal Facility in the Skou building at Department of Biomedicine, therefore it is only possible to scan animals from The Animal Facility at the moment. 

Contact

This imaging system is managed by the Bioimaging Core Facility at Department of Biomedicine. Please refer to the Bioimaging Core Facility's website for specifications, booking, training etc. and contact the Bioimaging Core Facility if you are interested in using the equipment.

The anesthesia required to image live animals is maintained and supported by The Animal Facility veterinarians. 

Survival procedures, mouse (1115-K23A)

Room 1115-K23A is used for survival procedures in mice, this could for example be treatment injections, simple surgeries, tumor measurements or general welfare and health checks on the mice that require thorough inspection of individual animals. The room contains three regular work benches, a work station with a downdraft table and a fume hood. The room will typically contain 2-3 mobile anesthesia units that can be moved around and adjusted to your needs. 

Contact

The room is maintained and managed by The Animal Facility and all work stations can be booked in Outlook. The work stations are listed under room number 1115-K23A. If you have questions for booking or resources in the rooms, please contact the veterinarians at vet.biomed@biomed.au.dk.

Survival procedures, rat (1115-K17)

Room 1115-K17 is used for survival procedures in rats, this could for example be treatment injections, simple surgeries, tumor measurements or general welfare and health checks on the rats that require thorough inspection of individual animals. The room contains three regular work benches, a work station with a downdraft table, a LAF bench and a fume hood. The room will typically contain 2 mobile anesthesia units that can be moved around and adjusted to your needs. 

Contact

The room is maintained and managed by The Animal Facility and all work stations can be booked in Outlook. The work stations are listed under room number 1115-K17. If you have questions for booking or resources in the rooms, please contact the veterinarians at vet.biomed@biomed.au.dk.

Tamoxifen room (1115-K17A)

In the 'Tamoxifen room' all mice are housed in single-use cages that can be disposed off directly after use. The room can be used when dosing animals with carcinogens, toxins, cytostic agents or similar agents that can pose a health hazard for personnel and sorroundings. Quarantine time can vary depending on what kind of hazardous drugs or reagents that is being used. 

Access to this room is restricted and it will require an access card valid to enter this room. Access is granted upon completion of a physical introduction to the room which will include information on proper dress code and additional PPE required, use of and housing in single-use cages, handling and packing of waste, use of fume hood and anesthesia setup etc.

Contact

The room is managed by animal caretakers Linda Lehmann Rasmussen (linda@biomed.au.dk) and Paw Vinther (paw@biomed.au.dk). Please contact either one to arrange an introduction and to make sure there is room for your mice before you move them. You can also contact Linda or Paw if anything is missing from the room (PPE, waste bins for hazardous waste etc.).

Contact

Please find contact information on who manages the equipment or rooms in the individual descriptions to the left.

How to book the rooms

Download the guide describing how to book rooms or resources in Outlook.