UNDINE
A unique multidisciplinary and translational research effort
We investigate the human genetics and immunology of SARS-CoV-2 from a personalised perspective, going all the way from single cells to the whole organism. We are building on established clinical cohorts of patients with different SARS-CoV-2 disease manifestations and employing state-of-the-art and innovative genetic, molecular and immunological strategies of investigation. Seven interrelated work packages (WP) have been designed to reach the research goals of the project:
WP1: Cohorts of SARS-CoV-2-infected subjects
WP2: Cellular models and immune responses to SARS-CoV-2 & variants of concern
WP3: Human genetic resistance to SARS-CoV-2 infection or disease
WP4: Human genetics and immunity of critical COVID-19 pneumonia
WP5: Cytokine autoantibodies in the pathogenesis of COVID-19
WP6: Human genetics and immunology of MIS-C/A and pernio
WP7: Human genetics and immunology of Long COVID
